Sporadic Meningioangiomatosis: Diagnosis with Computed Tomography and Magnetic Resonance Imaging

Abstract

Meningioangiomatosis (MA) is a rare, benign, hamartomatous lesion of leptomeninges and underlying cerebral cortex. Preoperative diagnosis is difficult and challenging due to its diverse clinical, pathological and imaging features. Imaging findings of this disease including computed tomography (CT) and magnetic resonance imaging (MRI) are reviewed in this chapter. CT findings include focal extensively calcified lesions, lesions with patchy calcification, and no apparent calcification. MRI findings include predominantly hypointensity on T1-weighted images and hyperintensity on T2-weighted images, and gyriform hyperintensity on FLAIR sequences. After contrast material administration, the majority of the lesions show heterogeneous enhancement. Occasionally, a non-enhancing lesion on MRI may be seen due to extensive calcification on CT. Gyriform hyperintensity on FLAIR sequence is the unique MRI feature of meningioangiomatosis, which correlates with proliferating microvessels with perivascular cuffs of spindle-cell proliferation within the cortex on pathology.