Summary
The principal findings and potential limitations of the St Thomas’ Atherosclerosis Regression Study (STARS) are presented. STARS was a randomized endpoint blinded study of the effects of lipid-lowering therapy on angiographic coronary artery disease (CAD) in male patients with hypercholesterolemia. Both a fat-modified diet and diet-plus cholestyramine favourably influenced the course of CAD over 3 years. As discussed in this paper, the study did, however, have some limitations in respect of its sample size, use of angiography and generalizability of the findings.
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Watts, G.F. (1996). The St Thomas’ Atherosclerosis Regression Study and an appraisal of its potential limitations. In: Bruschke, A.V.G., Reiber, J.H.C., Lie, K.I., Wellens, H.J.J. (eds) Lipid-Lowering Therapy and Progression of Coronary Atherosclerosis. Developments in Cardiovascular Medicine, vol 180. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0143-8_13
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DOI: https://doi.org/10.1007/978-94-009-0143-8_13
Publisher Name: Springer, Dordrecht
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