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Immobilized proteins as HPLC chiral stationary phases

  • Chapter
Chiral Liquid Chromatography

Abstract

Proteins are high-molecular-weight polymers composed of chiral subunits (L-amino acids). These polymers play a number of different roles in a biological system including the complexation (or binding) of xenobiotic materials. As proteins are chiral polymers, it is not surprising that the binding of small enantiomeric molecules is often stereospecific. This is especially true for the serum proteins α1-acid glycoprotein (AGP) and albumin (SA).

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Authors
  1. I. W. Wainer
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Editors and Affiliations

  1. School of Pharmaceutical and Chemical Sciences, University of Sunderland, Sunderland, UK

    W. J. Lough BSc, PhD, MRSC, C. Chem

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© 1989 Chapman & Hall

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Wainer, I.W. (1989). Immobilized proteins as HPLC chiral stationary phases. In: Lough, W.J. (eds) Chiral Liquid Chromatography. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-0861-1_7

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  • DOI: https://doi.org/10.1007/978-94-009-0861-1_7

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6875-8

  • Online ISBN: 978-94-009-0861-1

  • eBook Packages: Springer Book Archive

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