Skip to main content

Part of the book series: Topics in Molecular Organization and Engineering ((MOOE,volume 4))

  • 131 Accesses

Abstract

The atomic hypothesis, first formulated around 500 years B.C., was without influence on medicine, when empiricism was at a stage compared to superstition. Hippocrates, the master of Cos Island, and 600 years later Galen, in Rome, were the most famous men in medicine.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. A. F. Garrod: Inborn Errors of Metabolism. Reprinted by Harris, Oxford University Press (1963).

    Google Scholar 

  2. J. B. Stanbury, J. B. Wyngaarden, and D. S. Frederikson: The Metabolic Basis of Inherited Diseases. McGraw Hill, Toronto (1983).

    Google Scholar 

  3. D. J. Weatherhall: The New Genetics and Clinical Practice. Oxford University Press (1985).

    Google Scholar 

  4. M. F. Perutz: ‘Fundamental research on molecular biology relevant medicine’. Nature 262, 449 (1976).

    Article  CAS  Google Scholar 

  5. G. Schapira and J. C. Dreyfus: Pathologie moléculaire. Masson, Paris (1975).

    Google Scholar 

  6. F. Gros: Les secrets du gène. Ed. O. Jacob, Paris (1986).

    Google Scholar 

  7. L. Pauling and H. A. Itano: ‘Sickle-cell anemia: a molecular disease’. Science 110, 543–548 (1949).

    Article  CAS  Google Scholar 

  8. H. Wajcman and D. Labie: ‘Aspects actuels de la biologie de la drépanocytose’. Ann. Med. Int. 132, 548–594 (1981).

    Google Scholar 

  9. Y. W. Kan and A. M. Dozy: ‘Antenatal diagnosis of sickle-cell anemia by DNA analysis’. Lancet I, 910(1900).

    Google Scholar 

  10. D. Labie, C. Trougos, and H. Wajcman: ‘Les bases moléculaires des thalassémies’. Ann. Méd. Int. 136, 923–945 (1985).

    Google Scholar 

  11. D. J. Weatherhall and J. B. Clegg: The Thalassemia Syndromes. Blackwell Sc. Publ. (1981).

    Google Scholar 

  12. A. Kahn: ‘G6PD variants’. Hum. Gen. Sup. I, 37–44 (1978).

    Google Scholar 

  13. Y. Y. Hsia: ‘Detection and treatment of inborn errors of metabolism associated with mental deficiency’. Enzymes in Mental Health. Edited by C. J. Martin and B. Kiseh. J. B. Lippincott, Philadelphia (1966).

    Google Scholar 

  14. W. L. Nyhan: ‘Asbjorn Foiling and phenylketonuria’. T.I.B.S., 71 (1984).

    Google Scholar 

  15. S. C. Woo, A. S. Lidsky, F. Guttler, T. Chandrat, and R. Robson: ‘Cloned phenylalanine hydroxylase gene allows prenatal diagnosis’. Nature 306, 151–155 (1983).

    Article  CAS  Google Scholar 

  16. J. H. Dassault: ‘Hypothyroïdie congénitale’. Med. Sci. 1, 261–263 (1985).

    Google Scholar 

  17. V. E. Shih and H. I. Lévy: ‘Galactosemia screening of new born in Massachusetts’. N.E.M.J. 284,733–737(1971).

    Google Scholar 

  18. R. Mycrowitz and R. L. Proja: ‘cDNA clone for the αchain of human β hexoaminidase, deficiency of α chain mRNA in Aschkenazi Tay-Sachs fibroblasts’. P.N.A.S. 81, 5394–5398 (1984).

    Article  Google Scholar 

  19. P. Meyer: Hypertension artérielle. Flammarion, Paris (1978).

    Google Scholar 

  20. S. Gershon and B. Shopson: Lithium: its Role in Psychiatric Research and Treatment. Plenum (1973).

    Google Scholar 

  21. R. H. S. Thompson:Thiamine and the Metabolism of Pyruvate. T.I.B.S., 460 (1983).

    Google Scholar 

  22. A report of the surgeon general: smoking and health, 1979. US department of health. Education and welfare public health service, office of the assistant secretary for health.

    Google Scholar 

  23. C. S. Lieber: ‘The metabolism of alcohol’. Sci. Am. 234, 25–33 (1976).

    Article  CAS  Google Scholar 

  24. P. Leder: ‘The genetics of antibody diversity’. Sci. Am. 246, 72–83 (1981).

    Google Scholar 

  25. R. A. Lerner: ‘Synthetic vaccines’. Sci. Am. 248, 48–56 (1983).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1989 Kluwer Academic Publishers, Dordrecht, The Netherlands.

About this chapter

Cite this chapter

Schapira, G. (1989). The Adventure of Molecules in Pathology. In: Maruani, J. (eds) Molecules in Physics, Chemistry, and Biology. Topics in Molecular Organization and Engineering, vol 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1173-4_5

Download citation

  • DOI: https://doi.org/10.1007/978-94-009-1173-4_5

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-277-2599-8

  • Online ISBN: 978-94-009-1173-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics