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Eicosanoids and gastrointestinal motility

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Eicosanoids and the Gastrointestinal Tract

Part of the book series: Advances in Eicosanoid Research ((AEIR,volume 2))

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Abstract

The effect on gastrointestinal motility of prostaglandins, thromboxanes and more recently the leukotriene family has been enthusiastically researched ever since Kurzrok and Lieb1 first demonstrated the contractile effect of seminal ‘prostaglandin’ on the isolated rabbit gut preparation. In the space of the last fifty years the gastrointestinal tract has been shown to be an excellent source of the enzymes responsible for the synthesis and break-down of eicosanoids and this, coupled with their potent biological effects on gut motility and secretions, has prompted a search for their physiological role(s) in this part of the body.

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  1. Clinical Pharmacology Group Medical Faculty, University of Southampton, UK

    Keith Hillier (Senior Lecturer) (Senior Lecturer)

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Moore, P.K. (1988). Eicosanoids and gastrointestinal motility. In: Hillier, K. (eds) Eicosanoids and the Gastrointestinal Tract. Advances in Eicosanoid Research, vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-1281-6_8

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  • DOI: https://doi.org/10.1007/978-94-009-1281-6_8

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