Abstract
We have developed a fully integrated protein synthesis system including micropumps by using “Biochemical IC chips [1]” proposed by Ikuta. The built-in micropumps driven by shape memory alloy microactuators provide sufficiently long lifetime and flow rate to synthesize protein. The luminous protein “Luciferase” of firefly was successfully synthesized from DNA in seven hours with the built-in micropumps. The palm-top protein synthesis devices are promising and powerful tools for not only order-made examination but also implantable/wearable medical devices in the near future.
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References
K. Ikuta, Artificial life V (MIT press), p. 17 (1997).
K. Ikuta, K. Ikeda, A. Takahashi and S. Maruo, Proc. of µ-TAS 2001, p. 66 (2001).
K. Ikuta, S. Maruo, T. Fujisawa and A. Yamada, Proc. of MEMS 99, p. 376 (1999).
T. Hasegawa and K. Ikuta, Proc. of Micro Total Analysis Systems 2001, p.377 (2001).
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© 2002 Springer Science+Business Media Dordrecht
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Ikuta, K., Takahashi, A., Ikeda, K., Maruo, S. (2002). User-Assembly, Fully Integrated Micro Chemical Laboratory Using Biochemical IC Chips for Wearable/Implantable Applications. In: Baba, Y., Shoji, S., van den Berg, A. (eds) Micro Total Analysis Systems 2002. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0295-0_12
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DOI: https://doi.org/10.1007/978-94-010-0295-0_12
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-3952-9
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