Abstract
Desipramine is a tricyclic antidepressant with actions and uses similar to amitriptyline but with reduced sedating and antimuscarinic properties. It is the principal active metabolite of imipramine. The plasma half-life varies from 10 to 35 hours as a result of inter-subject variability in metabolism. The therapeutic range in plasma is 0.07-0.2 μg/ml. Monitoring is valuable only in patients with a diagnosis of endogenous depression.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1995 Springer Science+Business Media New York
About this chapter
Cite this chapter
Wilson, J.F. (1995). Desipramine. In: Wilson, J.F. (eds) Drugs Eicosanoids. Immunoassay Kit Directory, vol 1 / 3 / 4. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-0679-5_13
Download citation
DOI: https://doi.org/10.1007/978-94-011-0679-5_13
Publisher Name: Springer, Dordrecht
Print ISBN: 978-0-7923-8863-0
Online ISBN: 978-94-011-0679-5
eBook Packages: Springer Book Archive