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Platelet immunology: allo-antigens, transfusion

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The Role of Platelets in Blood-Biomaterial Interactions

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Abstract

Platelet transfusions were introduced in the early sixties. However they have only been developed when plastic bags could be used as blood containers. Another important step was achieved when cell separators have permit to obtain large amount from one blood donor. Platelet transfusions are now a common therapeutical approach of primary thrombocytopenia or cytopenia secondary to chemotherapy. Their development has pointed out two aspects: first the role of platelet alloantigen, second the importance of the technique used to collect platelet and the conditions of platelet storage.

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Authors and Affiliations

  1. Hématologie — Transfusion, Hôpital Lariboisière, 2 Rue Ambroise Paré, 75010, Paris, France

    B. Boval, J. P. Feugeas & J.-L. Wautier

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  1. B. Boval
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  2. J. P. Feugeas
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  3. J.-L. Wautier
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Editors and Affiliations

  1. Biomedical Engineering Laboratory, University of Patras, Rion, Patras, 26 100, Greece

    Y. F. Missirlis

  2. Laboratoire Central d’Immunohematologie, Hopital Lariboisiere, 2, rue Ambroise-Pare, 75010, Paris, France

    J.-L. Wautier

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Boval, B., Feugeas, J.P., Wautier, JL. (1993). Platelet immunology: allo-antigens, transfusion. In: Missirlis, Y.F., Wautier, JL. (eds) The Role of Platelets in Blood-Biomaterial Interactions. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-1745-6_3

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  • DOI: https://doi.org/10.1007/978-94-011-1745-6_3

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