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Californium-252 in the Treatment of Soft Tissue Sarcoma

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Californium-252 Isotope for 21st Century Radiotherapy

Part of the book series: NATO ASI Series ((ASHT,volume 29))

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Abstract

Soft tissue sarcomas are a heterozygous group of malignancies with various treatment related outcomes that are based on factors such as grade, histology, primary site among others [1–3]. Recent series including a randomized trial from Memorial Sloan Kettering has attempted to define the role of brachytherapy in the treatment of STS. However, as with most reviews this and other reported series are limited in the traditional use or radioactive source such as I-125 or Ir-192 [4–6]. In an effort to help overcome some of the limitations placed on traditional low dose rate brachytherapy, attempts at high dose rate or pulsed high dose rate brachytherapy have been reported [7–8]. During the past thirty years, a remarkable radioactive source (Cf-252) introduced which may offer preferential benefits when compared to the traditionally utilized radiation sources. Although it has been clinically used and described in various sites such as cervix, head and neck, and brain, little has been described in its use for the treatment of STS [9–11].

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© 1997 Springer Science+Business Media Dordrecht

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Fontanesi, J., Zalupski, M., Chuba, P., Wierzbicki, J.G., Rivard, M.J., Ryan, J. (1997). Californium-252 in the Treatment of Soft Tissue Sarcoma. In: Wierzbicki, J.G. (eds) Californium-252 Isotope for 21st Century Radiotherapy. NATO ASI Series, vol 29. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5766-7_16

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  • DOI: https://doi.org/10.1007/978-94-011-5766-7_16

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6433-0

  • Online ISBN: 978-94-011-5766-7

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