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Observation and Interpretation of Residual Dipolar Couplings in Biomolecules

  • Chapter
NMR of Ordered Liquids

Abstract

Residual dipolar couplings were introduced a few years ago as a new type of constraint in biomolecular structure determination. Thereafter, the field has literally exploded, with over a hundred and fifty articles published since 1995. The method is increasingly popular because of the relative ease with which spectral measurements can be made compared to NOE analysis, and the high amount of information about structure and dynamics of macromolecules that can be extracted.

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Authors and Affiliations

  1. Biochemistry Department, McGill University, Montreal, Quebec, Canada

    Jean-François Trempe & Kalle Gehring

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  1. Jean-François Trempe
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  1. University of British Columbia, Canada

    E. Elliott Burnell

  2. University of Amsterdam, The Netherlands

    Cornelis A. de Lange

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Trempe, JF., Gehring, K. (2003). Observation and Interpretation of Residual Dipolar Couplings in Biomolecules. In: Burnell, E.E., de Lange, C.A. (eds) NMR of Ordered Liquids. Springer, Dordrecht. https://doi.org/10.1007/978-94-017-0221-8_8

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  • DOI: https://doi.org/10.1007/978-94-017-0221-8_8

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