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Primary Surgical Treatment of Epithelial Ovarian Cancer

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Frontiers in Ovarian Cancer Science

Part of the book series: Comprehensive Gynecology and Obstetrics ((CGO))

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Abstract

The main purpose of primary surgery for ovarian cancer is to eradicate the tumor completely because the postoperative residual tumor diameter is correlated with the prognosis. Surgery after neoadjuvant chemotherapy should be considered for patients with advanced cancer in whom complete tumor resection cannot be expected because of extensive peritoneal spread as well as patients whose general condition is poor. Recently it is also an acceptable alternative for women with potentially resectable disease who prefer the neoadjuvant approach because neoadjuvant chemotherapy plus subsequent surgery is not inferior to primary surgery in terms of progression-free survival or overall survival. Centralizing the primary care of advanced ovarian cancer to high-volume hospitals also increases the frequency of achieving complete cytoreduction with surgery and significantly improves survival. Although lymphadenectomy is essential for accurate staging of patients, there have been no reports showing therapeutic efficacy of lymphadenectomy. We are waiting for the results of Arbeitsgemeinschaft Gynäkologische Onkologie (AGO) clinical studies to decide the role of lymphadenectomy in advanced ovarian cancer.

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Authors and Affiliations

  1. Department of Obstetrics and Gynecology, School of Medicine, Tokai University, Tokyo, Japan

    Mikio Mikami M.D., Ph.D.

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  1. Mikio Mikami M.D., Ph.D.
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Correspondence to Mikio Mikami M.D., Ph.D. .

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Editors and Affiliations

  1. Department of Obstetrics and Gynecology, Kumamoto University, Kumamoto, Japan

    Hidetaka Katabuchi

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Mikami, M. (2017). Primary Surgical Treatment of Epithelial Ovarian Cancer. In: Katabuchi, H. (eds) Frontiers in Ovarian Cancer Science. Comprehensive Gynecology and Obstetrics. Springer, Singapore. https://doi.org/10.1007/978-981-10-4160-0_11

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  • DOI: https://doi.org/10.1007/978-981-10-4160-0_11

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