Abstract
Metagenomics or community genomics refers to the study of genomic DNA of any culture-independent analysis of microbial communities. Non-culturable microbial groups represent the huge majority of global microorganisms. Microbial populations present in every biological niche even humans body carry 10 times more bacterial cells and 100 times more bacterial genes than its own cells and genes. Microbes also hold the secret key for generating renewable biofuels and bioremediation. The next-generation sequencing (NGS) technology provides advantage of parallel sequencing of thousands of sequence from any samples including environmental and clinical without cultivation of it. High-throughput data generated by NGS provides information about vibrant nature of microbial populations and its effect on the atmosphere and health. So, advantages of next-generation sequencing (NGS) technology make metagenomics among the fastest growing research field. In this chapter, we tried to explain the advancement in NGS technology as well as its suitability and approaches to explore metagenomics.
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Thakkar, J.R., Sabara, P.H., Koringa, P.G. (2017). Exploring Metagenomes Using Next-Generation Sequencing. In: Singh, R., Kothari, R., Koringa, P., Singh, S. (eds) Understanding Host-Microbiome Interactions - An Omics Approach. Springer, Singapore. https://doi.org/10.1007/978-981-10-5050-3_3
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DOI: https://doi.org/10.1007/978-981-10-5050-3_3
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