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Infections of the Lacrimal Drainage System

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Principles and Practice of Lacrimal Surgery

Abstract

The canaliculi and the lacrimal sac are those segments of lacrimal drainage system, which are prone for infections, and these are not uncommon in an ophthalmic plastics practice. This chapter focuses on infective canaliculitis and dacryocystitis and their diagnosis, microbial profiles, managements, and outcomes.

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References

  1. Anand S, Hollingworth K, Kumar V, et al. Canaliculitis: the incidence of long-term epiphora following canaliculotomy. Orbit. 2004;23:19–26.

    Article  PubMed  Google Scholar 

  2. Demant E, Hurwitz JJ. Canaliculitis: review of 12 cases. Can J Ophthalmol. 1980;15:73–5.

    CAS  PubMed  Google Scholar 

  3. Kaliki S, Ali MJ, Honavar SG, et al. Primary canaliculitis: clinical features, microbiological profile, and management outcome. Ophthal Plast Reconstr Surg. 2012;28:355–60.

    Google Scholar 

  4. Vécsei VP, Huber-Spitzy V, Arocker-Mettinger E, et al. Canaliculitis: difficulties in diagnosis, differential diagnosis and comparison between conservative and surgical treatment. Ophthalmologica. 1994;208:314–7.

    Article  PubMed  Google Scholar 

  5. Brazier JS, Hall V. Propionibacterium propionicum and infections of the lacrimal apparatus. Clin Infect Dis. 1993;17:892–3.

    Article  CAS  PubMed  Google Scholar 

  6. McKellar MJ, Aburn NS. Cast-forming Actinomyces israelii canaliculitis. Aust N Z J Ophthalmol. 1997;25:301–3.

    Article  CAS  PubMed  Google Scholar 

  7. Sullivan TJ, Hakin KN, Sathananthan N, et al. Chronic canaliculitis. Aust N Z J Ophthalmol. 1993;21:273–4.

    Article  CAS  PubMed  Google Scholar 

  8. Mohan ER, Kabra S, Udhay P, et al. Intracanalicular antibiotics may obviate the need for surgical management of chronic suppurative canaliculitis. Indian J Ophthalmol. 2008;56:338–40.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Briscoe D, Edelstein E, Zacharopoulos I, et al. Actinomyces canaliculitis: diagnosis of a masquerading disease. Graefes Arch Clin Exp Ophthalmol. 2004;242:682–6.

    Article  PubMed  Google Scholar 

  10. Hussain I, Bonshek RE, Loudon K, et al. Canalicular infection caused by Actinomyces. Eye. 1993;7:542–4.

    Article  PubMed  Google Scholar 

  11. Asghar S, Mahmood A, Khan MA. Nocardia canaliculitis presenting as pouted punctum. J Coll Physicians Surg Pak. 2008;18:55–7.

    PubMed  Google Scholar 

  12. Bharathi MJ, Ramakrishnan R, Meenakshi R, et al. Nocardia asteroides canaliculitis: a case report of uncommon aetiology. Indian J Med Microbiol. 2004;22:123–5.

    CAS  PubMed  Google Scholar 

  13. Singh CN, Thakker M, Sires BS. Pyogenic granuloma associated with chronic Actinomyces canaliculitis. Ophthal Plast Reconstr Surg. 2006;22:224–45.

    Article  PubMed  Google Scholar 

  14. Eloy P, Brandt H, Nollevaux MC, et al. Solid cast-forming actinomycotic canaliculitis: case report. Rhinology. 2004;42:103–6.

    PubMed  Google Scholar 

  15. Seal DV, McGill J, Flanagan D, et al. Lacrimal canaliculitis due to Arachnia (Actinomyces) propionica. Br J Ophthalmol. 1981;65:10–3.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Joseph TA, Paniker CK, Kumari S, et al. Actinomycotic lacrimal canaliculitis. Indian J Ophthalmol. 1980;28:157–9.

    CAS  PubMed  Google Scholar 

  17. Fowler AM, Dutton JJ, Fowler WC, et al. Mycobacterium chelonae canaliculitis associated with SmartPlug use. Ophthal Plast Reconstr Surg. 2008;24:241–3.

    Article  PubMed  Google Scholar 

  18. Leung DY, Kwong YY, Ma CH, et al. Canaliculitis associated with a combined infection of Lactococcus lactis cremoris and Eikenella corrodens. Jpn J Ophthalmol. 2006;50:284–5.

    Article  PubMed  Google Scholar 

  19. de Koning EW, van Bijsterveld OP. Herpes simplex virus canaliculitis. Ophthalmologica. 1983;186:173–6.

    Article  PubMed  Google Scholar 

  20. Jordan DR, Agapitos PJ, McCunn PD. Eikenella corrodens canaliculitis. Am J Ophthalmol. 1993;115:823–4.

    Article  CAS  PubMed  Google Scholar 

  21. Chumbley LC. Canaliculitis caused by Enterobacter cloacae: report of a case. Br J Ophthalmol. 1984;68:364–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  22. Romano A, Segal E, Blumenthal M. Canaliculitis with isolation of Pityrosporum pachydermatis. Br J Ophthalmol. 1978;62:732–4.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  23. Newton JC, Tulevech CB. Lacrimal canaliculitis due to Candida albicans. Report of a case and a discussion of its significance. Am J Ophthalmol. 1962;53:933–6.

    Article  CAS  PubMed  Google Scholar 

  24. Weinberg RJ, Sartoris MJ, Buerger GF Jr, et al. Fusobacterium in presumed Actinomyces canaliculitis. Am J Ophthalmol. 1977;84:371–4.

    Article  CAS  PubMed  Google Scholar 

  25. Ali MJ, Pujari A, Motukupally S, et al. Kocuria rosea canaliculitis: a clinicomicrobiological correlation. Ophthal Plast Reconstr Surg. 2014;30:e139–40.

    Google Scholar 

  26. Sathananthan N, Sullivan TJ, Rose GE, et al. Intubation dacryocystography in patients with a clinical diagnosis of chronic canaliculitis (“streptothrix”). Br J Radiol. 1993;66:389–93.

    Article  CAS  PubMed  Google Scholar 

  27. Hurwitz JJ, Pavlin CJ. Proximal canalicular imaging utilizing ultrasound biomicroscopy B: Canaliculitis. Orbit. 1998;17:31–6.

    Article  PubMed  Google Scholar 

  28. Moscato EE, Sires BS. Atypical canaliculitis. Ophthal Plast Reconstr Surg. 2008;24:54–5.

    Article  PubMed  Google Scholar 

  29. Charles NC, Lisman RD, Mittal KR. Carcinoma of the lacrimal canaliculus masquerading as canaliculitis. Arch Ophthalmol. 2006;124:414–6.

    Article  PubMed  Google Scholar 

  30. Fulmer NL, Neal JG, Bussard GM, et al. Lacrimal canaliculitis. Am J Emerg Med. 1999;17:385–6.

    Article  CAS  PubMed  Google Scholar 

  31. Pavilack MA, Frueh BR. Through curettage in the treatment of chronic canaliculitis. Arch Ophthalmol. 1992;110:200–2.

    Article  CAS  PubMed  Google Scholar 

  32. Lin SC, Kao SC, Tsai CC, et al. Clinical characteristics and factors associated the outcome of lacrimal canaliculitis. Acta Ophthalmol. 2011;89:759–63.

    Article  PubMed  Google Scholar 

  33. Lee MJ, Choung HK, Kim NJ, et al. One-snip punctoplasty and canalicular curettage through the punctum: a minimally invasive surgical procedure for primary canaliculitis. Ophthalmology. 2009;116:2027–30.e2.

    Article  PubMed  Google Scholar 

  34. Ali MJ, Joshi DS, Naik MN, et al. Clinical profile and management outcome of acute dacryocystitis: two decades of experience in a tertiary eye care center. Semin Ophthalmol. 2015;30:118–23.

    Google Scholar 

  35. Cahill KV, Burns JA. Management of acute dacryocystitis in adults. Ophthal Plast Reconstr Surg. 1993;9:38–42.

    Article  CAS  PubMed  Google Scholar 

  36. Mills DM, Bodman MG, Meyer DR, et al. The microbiologic spectrum of acute dacryocystitis. A national study of acute versus chronic infection. Ophthal Plast Reconstr Surg. 2007;23:302–6.

    Article  PubMed  Google Scholar 

  37. Razavi ME, Ansari-Astaneh MR, Farzadnia M, et al. Bacteriological evaluation of adult dacryocystitis in Iran. Orbit. 2010;29:286–90.

    Article  PubMed  Google Scholar 

  38. Ali MJ, Motukupally SR, Joshi SD, et al. The microbiological profile of lacrimal abscess: two decades of experience from a tertiary eye care center. J Ophthalmic Inflamm Infect. 2013;3:57–61.

    Google Scholar 

  39. Manderwad GP, Kodiganti M, Ali MJ. Cardiobacterium hominis-induced acute dacryocystitis and lacrimal abscess. Indian J Ophthalmol. 2014;62:495–7.

    Google Scholar 

  40. Huber-Spitzy V, Steinkogler FJ, Huber E, et al. Acute dacryocystitis: microbiology and conservative therapy. Acta Ophthalmol. 1992;70:745–9.

    Article  CAS  Google Scholar 

  41. Kikkawa DO, Heinz GW, Martin RT, et al. Orbital cellulitis and abscess secondary to dacryocystitis. Arch Ophthalmol. 2002;120:1096–9.

    PubMed  Google Scholar 

  42. Warrak E, Khoury P. Orbital abscess secondary t 243 o acute dacryocystitis. Can J Ophthalmol. 1996;31:201–2.

    CAS  PubMed  Google Scholar 

  43. Mauriello JA, Wasserman BA. Acute dacryocystitis: an unusual case of life threatening orbital intraconal abscess with frozen globe. Ophthal Plast Reconstr Surg. 1996;12:294–5.

    Article  PubMed  Google Scholar 

  44. Maheshwari R, Maheshwari S, Shah T. Acute dacryocystitis causing orbital cellulitis and abscess. Orbit. 2009;28:196–9.

    Article  PubMed  Google Scholar 

  45. Schmitt NJ, Beatty RL, Kennerdell JS. Superior ophthalmic vein thrombosis in a patient with dacryocystitis induced orbital cellulitis. Ophthal Plast Reconstr Surg. 2005;21:387–9.

    Article  PubMed  Google Scholar 

  46. Wu W, Yan W, MacCallum JK, et al. Primary treatment of acute dacryocystitis by endoscopic dacryocystorhinostomy with silicone intubation guided by a soft probe. Ophthalmology. 2009;116:116–22.

    Article  PubMed  Google Scholar 

  47. Lee TS, Woog JJ. Endonasal dacryocystorhinostomy in 261 the primary treatment of acute dacryocystitis with abscess formation. Ophthal Plast Reconstr Surg. 2001;17:180–3.

    Article  CAS  PubMed  Google Scholar 

  48. Ali MJ, Alam SM, Naik MN. Dacryoendoscopic features in a case of canaliculitis with concretions. Ophthal Plast Reconstr Surg. 2017;33(3):228–9. (Epub)

    Google Scholar 

  49. Anand S, Hollingworth K, Kumar V, et al. Canaliculitis: the incidence of long-term epiphora following canaliculotomy. Orbit. 2004;12:19–26.

    Article  Google Scholar 

  50. Perumal B, Meyer DR. Vertical canaliculotomy with retrograde expression of concretions for the treatment of canaliculitis. Ophthal Plast Reconstr Surg. 2015;31:119–21.

    Article  PubMed  Google Scholar 

  51. Kim UR, Wadwekar B, Prajna L. Primary canaliculitis: the incidence, clinical features, outcome, and long-term epiphora after snip-punctoplasty and curettage. Saudi J Ophthalmol. 2015;29:274–7.

    Article  PubMed  PubMed Central  Google Scholar 

  52. Zhang Q, Xu B, Li XX, et al. Clinical characteristics, treatment patterns, and outcomes of primary canaliculitis among patients in Beijing. China Biomed Res Int. 2015;2015:904756.

    PubMed  Google Scholar 

  53. Perumal B, Carlson JA, Meyer DR. A pathological analysis of canaliculitis concretions: more than just Actinomycetes. Scientifica. 2016;2016:6313070.

    Article  PubMed  PubMed Central  Google Scholar 

  54. Huang YY, Yu WK, Tsai CC, et al. Clinical features, microbiological profiles and treatment outcome of lacrimal plug-related canaliculitis compared to those of primary canaliculitis. Br J Ophthalmol. 2016;100:1285–9.

    Article  PubMed  Google Scholar 

  55. Foveau P, George JL, Cloche V, et al. Actinomyces canaliculitis as a complication of silicone lacrimal punctal plug. J Fr Ophthalmol. 2015;38:e51–3.

    Article  CAS  Google Scholar 

  56. Klein-Theyer A, Boldin I, Rabensteiner DF, et al. Prevalence of canaliculitis after Smartplug insertion during long-term follow up. Br J Ophthalmol. 2015;99:1134–6.

    Article  PubMed  Google Scholar 

  57. Boulze-Pankert M, Roux C, Nkamga VD, et al. Aggregatibacter aphrophilus chronic lacrimal canaliculitis: a case report. BMC Ophthalmol. 2016;106(16):132–4.

    Article  Google Scholar 

  58. Ali MJ, Joseph J, Sharma S, et al. Canaliculitis with isolation of Myroides species. Ophthal Plast Reconstr Surg. 2015;33(3S Suppl 1):S24–5. (Epub)

    Google Scholar 

  59. Rocke J, Roydhouse T, Spencer T. Canaliculitis caused by Citrobacter freundii. Clin Exp Ophthalmol. 2016;44:856–8.

    Article  PubMed  Google Scholar 

  60. Chu HS, Chang SC, Shen EP, et al. Nontuberculous mycobacterial ocular infections- comparing the clinical and microbiological characteristics between Mycobacterium abscessus and Mycobacterium massiliense. PLoS One. 2015;10:e0116236.

    Article  PubMed  PubMed Central  Google Scholar 

  61. Ali MJ. Pediatric acute dacryocystitis. Ophthal Plast Reconstr Surg. 2015;31:341–7.

    Google Scholar 

  62. Ganguly A, Ali MJ, Padmaja K, et al. Bacteremia following nasolacrimal duct probing: is there a role of pre-operative antibiotic prophylaxis? Ophthal Plast Reconstr Surg. 2016;32:90–2.

    Google Scholar 

  63. Martin G, Pon A, Robert M, et al. Acute dacryocystitis and infectious mononucleosis: an association not to be missed. J Fr Ophthalmol. 2015;38:e245–6.

    Article  CAS  Google Scholar 

  64. Mishra DK, Ali MJ, Bhargava A, et al. Acute dacryocystitis as a presenting sign of chronic lymphocytic leukemia. Clin Exp Ophthalmol. 2016;44:67–9.

    Google Scholar 

  65. Lombardi D, Mattavelli D, Accorona R, et al. Acute dacryocystitis with empyema of the lacrimal sac. Is immediate endoscopic dacryocystorhinostomy justified? Otolaryngol Head Neck Surg. 2014;150:1071–7.

    Article  PubMed  Google Scholar 

  66. Kamal S, Ali MJ, Pujari A, et al. Primary powered endoscopic dacryocystorhinostomy in the setting of acute dacryocystitis and lacrimal abscess. Ophthal Plast Reconstr Surg. 2015;31:293–5.

    Google Scholar 

  67. Chisty N, Singh M, Ali MJ, et al. Long-term outcomes of powered endoscopic dacryocystorhinostomy in acute dacryocystitis. Laryngoscope. 2016;126:551–3.

    Google Scholar 

  68. Jain S, Ganguly A, Singh S, et al. Primary non-endoscopic endonasal versus delayed external dacryocystorhinostomy in acute dacryocystitis. Ophthal Plast Reconstr Surg. 2016;33(4):285–8. (Epub)

    Article  Google Scholar 

  69. Kamal S, Ali MJ, Nair AG. Outcomes of endoscopic dacryocystorhinostomy: experience of a fellowship trainee at a tertiary care center. Indian J Ophthalmol. 2016;64:648–53.

    Google Scholar 

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Correspondence to Mohammad Javed Ali F.R.C.S .

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Pujari, A., Ali, M.J. (2018). Infections of the Lacrimal Drainage System. In: Ali, M. (eds) Principles and Practice of Lacrimal Surgery. Springer, Singapore. https://doi.org/10.1007/978-981-10-5442-6_17

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  • DOI: https://doi.org/10.1007/978-981-10-5442-6_17

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