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Prenatal Pesticide Exposure and Child Health

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Early-life Environmental Exposure and Disease

Abstract

This chapter presents evidence of the associations between prenatal pesticide exposure and adverse effects on child health and development. Contemporary studies of prenatal pesticide exposure and neurodevelopment, obesity, preterm birth/fetal growth, congenital abnormalities, and childhood cancers are reviewed here. The strongest evidence presented here comes from studies where biomarkers of exposure were used to assess exposure at multiple time points. Many of the studies discussed within this chapter are limited by nonspecific exposure assessments and cross-sectional study designs that do not account for temporal variability in pesticide exposure or identify sensitive windows of susceptibility during gestation. Longitudinal studies that measure exposure at multiple potentially sensitive time points and exposure to multiple pesticides simultaneously are needed before any conclusions regarding causation can be drawn. Still, given the nearly ubiquitous exposure to pesticides among the general population, the vulnerability of fetuses, and the potential for long-term effects on health and development, efforts to reduce pesticide exposure as a precaution among pregnant women are warranted.

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Silver, M.K., Meeker, J.D. (2020). Prenatal Pesticide Exposure and Child Health. In: Xia, Y. (eds) Early-life Environmental Exposure and Disease. Springer, Singapore. https://doi.org/10.1007/978-981-15-3797-4_3

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