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Flavonoids for Therapeutic Applications

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Plant Metabolites: Methods, Applications and Prospects

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Abstract

Flavonoids constitute a large group of plant phenolic metabolites with diverse structural compounds exhibiting multiple biological activities. Flavonoids have been used over centuries in folk medicine for tackling various human ailments and promoting the human health. With centuries old historical background, flavonoids still hold the valour to be captivated by researchers and clinicians for reframing the current medications to recuperate the equilibrium in human health. In this context, a vast range of biological activities of flavonoids has been documented by various research groups. These findings unwind the multi-targeting potential of flavonoids in various clinical conditions, which hints the ability of flavonoids to gratify the need of current treatment strategy mandating the handling of other complications accompanying a diseased condition. Moreover, the ubiquitous dietary sources of flavonoids underscore their innocuous nature as well as the likelihood to be used in clinical settings. This also enlightens that daily consumption of flavonoids from various dietary sources could act as better nutraceuticals for nourishing the health and assist the risk management of many complications. With this, a comprehensive overview on therapeutic applications of multipotent flavonoids has been provided in this chapter.

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Acknowledgement

The authors thankfully acknowledge the support extended by DST-FIST [Grant No. SR/FST/LSI-639/2015(C)], UGC-SAP [Grant No. F.5-1/2018/DRS-II (SAP-II)] and DST-PURSE [Grant No. SR/PURSE Phase 2/38 (G)]. The authors sincerely acknowledge the computational and bioinformatics facility provided by Bioinformatics Infrastructure Facility (funded by DBT, GOI; File No. BT/BI/25/012/2012, BIF). SKP is thankful to UGC for Mid-Career Award [F.19-225/2018(BSR)] and RUSA 2.0 [F.24-51/2014-U, Policy (TN Multi-Gen), Dept. of Edn, GoI].

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  1. Thirukannamangai Krishnan Swetha and Arumugam Priya contributed equally.

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  1. Department of Biotechnology, Science Campus, Alagappa University, Karaikudi, Tamil Nadu, India

    Thirukannamangai Krishnan Swetha, Arumugam Priya & Shunmugiah Karutha Pandian

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  1. Thirukannamangai Krishnan Swetha
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  1. Department of Botany, University of Kerala, Thiruvananthapuram, Kerala, India

    Swapna Thacheril Sukumaran

  2. Division of Microbiology, KSCSTE—Jawaharlal Nehru Tropical Botanic Garden and Research Institute, Thiruvananthapuram, Kerala, India

    Shiburaj Sugathan

  3. Department of Biotechnology and Microbiology, Kannur University, Kannur, Kerala, India

    Sabu Abdulhameed

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Swetha, T.K., Priya, A., Pandian, S.K. (2020). Flavonoids for Therapeutic Applications. In: Sukumaran, S.T., Sugathan, S., Abdulhameed, S. (eds) Plant Metabolites: Methods, Applications and Prospects. Springer, Singapore. https://doi.org/10.1007/978-981-15-5136-9_15

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