Skip to main content

3D-CNN Based Computer-Aided Diagnosis (CADx) for Lung Nodule Diagnosis

  • Conference paper
  • First Online:
Cognitive Cities (IC3 2019)

Part of the book series: Communications in Computer and Information Science ((CCIS,volume 1227))

Included in the following conference series:

  • 1468 Accesses

Abstract

For the lung nodule screening, one of the commonly testing methods is the chest radiograph. However, it is difficult to judge with the naked eye with the initial nodule size is usually less than one centimeter. It is known that skilled pulmonary radiologists have a high degree of accuracy in diagnosis, but there remain problems in disease diagnosis. These problems include the miss rate for diagnosis of small nodules and the diagnosis of change in preexisting interstitial lung disease. The recent studies have found that 68% lung cancer nodules in radiographs can be detected by one reader and 82% by two readers. In order to solve this problem, we proposed a 3D-CNN predicting model to differ malignant nodules from all nodules in computed tomography scan. In the experiment results, the model was able to achieve a training accuracy of 100% and a testing accuracy of 94.52%. It shows the proposed model is able to be used for improving the accuracy of detecting nodules.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Heelan, R.T., et al.: Non-small-cell lung cancer: results of the New York screening program. Radiology 151, 289–293 (1984)

    Article  Google Scholar 

  2. Stitik, F.P., Tockman, M.S., Khouri, N.F.: Screening for cancer. In: Chest Radiology, pp. 163–191 (1985)

    Google Scholar 

  3. Lo, S.-C., Lou, S.-L., Lin, J.-S., Freedman, M.T., Chien, M.V., Mun, S.K.: Artificial convolution neural network techniques and applications for lung nodule detection. IEEE Trans. Med. Imaging 14, 711–718 (1995)

    Article  Google Scholar 

  4. Brenner, D.J., Hall, E.J.: Computed tomography—an increasing source of radiation exposure. N. Engl. J. Med. 357, 2277–2284 (2007)

    Article  Google Scholar 

  5. VanGinneken, B., Setio, A.A.A., Jacobs, C., Ciompi, F.: Off-the-shelf convolutional neural network features for pulmonary nodule detection in computed tomography scans. In: 2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI), pp. 286–289 (2015)

    Google Scholar 

  6. Zhou, Z.-H., Jiang, Y., Yang, Y.-B., Chen, S.-F.: Lung cancer cell identification based on artificial neural network ensembles. Artif. Intell. Med. 24, 25–36 (2002)

    Article  Google Scholar 

  7. Sun, W., Zheng, B., Qian, W.: Computer aided lung cancer diagnosis with deep learning algorithms. In: Medical Imaging 2016: Computer-Aided Diagnosis, p. 97850Z (2016)

    Google Scholar 

  8. Ciompi, F., et al.: Towards automatic pulmonary nodule management in lung cancer screening with deep learning. Sci. Rep. 7, 46479 (2017)

    Article  Google Scholar 

  9. Rossetto, A.M., Zhou, W.: Deep learning for categorization of lung cancer CT images. In: Proceedings of the Second IEEE/ACM International Conference on Connected Health: Applications, Systems and Engineering Technologies, pp. 272–273 (2017)

    Google Scholar 

  10. Alakwaa, W., Nassef, M., Badr, A.: Lung cancer detection and classification with 3D convolutional neural network (3D-CNN). Lung Cancer 8(8), 409 (2017)

    Google Scholar 

  11. Chen, L., Wu, Y., DSouza, A.M., Abidin, A.Z., Wismüller, A., Xu, C.: MRI tumor segmentation with densely connected 3D CNN. In: Medical Imaging 2018: Image Processing, pp. 105741F (2018)

    Google Scholar 

  12. Wang, H.: Deep Convolutional Neural Networks for, pp. 1–9 (2009). https://doi.org/10.1007/978-3-319-44781-0

  13. Wang, G., Li, W., Ourselin, S., Vercauteren, T.: Automatic brain tumor segmentation using cascaded anisotropic convolutional neural networks. In: Crimi, A., Bakas, S., Kuijf, H., Menze, B., Reyes, M. (eds.) BrainLes 2017. LNCS, vol. 10670, pp. 178–190. Springer, Cham (2018). https://doi.org/10.1007/978-3-319-75238-9_16

    Chapter  Google Scholar 

  14. Zhao, C., Han, J., Jia, Y., Gou, F.: Lung nodule detection via 3D U-Net and contextual convolutional neural network. In: 2018 International Conference on Networking and Network Applications (NaNA), pp. 356–361 (2018)

    Google Scholar 

  15. Shaziya, H., Shyamala, K., Zaheer, R.: Automatic lung segmentation on thoracic CT scans using U-Net convolutional network. In: 2018 International Conference on Communication and Signal Processing (ICCSP), pp. 643–647 (2018)

    Google Scholar 

  16. Yaniv, Z., Lowekamp, B.C., Johnson, H.J., Beare, R.: SimpleITK image-analysis notebooks: a collaborative environment for education and reproducible research. J. Digit. Imaging 31(3), 290–303 (2017). https://doi.org/10.1007/s10278-017-0037-8

    Article  Google Scholar 

  17. Kuan, K., et al.: Deep learning for lung cancer detection: tackling the Kaggle data science bowl 2017 challenge. arXiv Preprint arXiv:1705.09435 (2017)

  18. Kumar, M.N.A., Sheshadri, H.S.: On the classification of imbalanced datasets. Int. J. Comput. Appl. 44, 1–7 (2012). https://doi.org/10.5120/6280-8449

    Article  Google Scholar 

  19. Alfaro-Cid, E., Sharman, K., Esparcia-Alcázar, A.I.: A genetic programming approach for bankruptcy prediction using a highly unbalanced database. In: Giacobini, M. (ed.) EvoWorkshops 2007. LNCS, vol. 4448, pp. 169–178. Springer, Heidelberg (2007). https://doi.org/10.1007/978-3-540-71805-5_19

    Chapter  Google Scholar 

  20. Maimon, O., Rokach, L. (eds.): Data Mining and Knowledge Discovery Handbook, 2nd edn. Springer, New York (2010). https://doi.org/10.1007/978-0-387-09823-4

    Book  MATH  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Tzu-Chi Tai .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Singapore Pte Ltd.

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

Tai, TC., Tian, M., Cho, WT., Lai, CF. (2020). 3D-CNN Based Computer-Aided Diagnosis (CADx) for Lung Nodule Diagnosis. In: Shen, J., Chang, YC., Su, YS., Ogata, H. (eds) Cognitive Cities. IC3 2019. Communications in Computer and Information Science, vol 1227. Springer, Singapore. https://doi.org/10.1007/978-981-15-6113-9_5

Download citation

  • DOI: https://doi.org/10.1007/978-981-15-6113-9_5

  • Published:

  • Publisher Name: Springer, Singapore

  • Print ISBN: 978-981-15-6112-2

  • Online ISBN: 978-981-15-6113-9

  • eBook Packages: Computer ScienceComputer Science (R0)

Publish with us

Policies and ethics