Abstract
Fine needle aspiration cytology (FNAC) is an essential technique for the diagnosis and management of thyroid lesions. FNAC helps in the selection of cases for further surgical excision. This chapter discusses the FNAC of the various thyroid lesions, along with the differential diagnosis.
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References
Galloway JW, Sardi A, DeConti RW, Mitchell WT Jr, Bolton JS. Changing trends in thyroid surgery. 38 years’ experience. Am Surg. 1991;57(1):18–20.
Hamberger B, Gharib H, Melton LJ 3rd, Goellner JR, Zinsmeister AR. Fine-needle aspiration biopsy of thyroid nodules. Impact on thyroid practice and cost of care. Am J Med. 1982;73(3):381–4.
Cibas ES. Ali SZ; NCI thyroid FNA state of the science conference. The Bethesda system for reporting thyroid cytopathology. Am J Clin Pathol. 2009 Nov;132(5):658–65.
Baloch ZW, LiVolsi VA, Asa SL, et al. Diagnostic terminology and morphologic criteria for cytologic diagnosis of thyroid lesions: a synopsis of the National Cancer Institute thyroid fine-needle aspiration state of the science conference. Diagn Cytopathol. 2008;36(6):425–37.
Harach HR, Zusman SB, Saravia DE. Nodular goiter: a histo-cytological study with some emphasis on pitfalls of fine-needle aspiration cytology. Diagn Cytopathol. 1992;8(4):409–19.
Faquin WC, Cibas ES, Renshaw AA. "atypical" cells in fine-needle aspiration biopsy specimens of benign thyroid cysts. Cancer. 2005;105(2):71–9.
Centeno BA, Szyfelbein WM, Daniels GH, Vickery AL Jr. Fine needle aspiration biopsy of the thyroid gland in patients with prior Graves’ disease treated with radioactive iodine. Morphologic findings and potential pitfalls. Acta Cytol. 1996;40(6):1189–97.
Jayaram G, Marwaha RK, Gupta RK, Sharma SK. Cytomorphologic aspects of thyroiditis. A study of 51 cases with functional, immunologic and ultrasonographic data. Acta Cytol. 1987;31(6):687–93.
Lamichaney R, Sherpa M, Das D, Bhutia CT, Laishram S. Fine-needle aspiration of De Quervain’s thyroiditis (subacute granulomatous thyroiditis): a cytological review of 20 cases. J Clin Diagn Res. 2017 Aug;11(8):EC09–11.
Anila KR, Nayak N, Jayasree K. Cytomorphologic spectrum of lymphocytic thyroiditis and correlation between cytological grading and biochemical parameters. J Cytol. 2016 Jul-Sep;33(3):145–9.
Lloyd RV, Osamura RY, Kloppel G. Rosai J (editors) € WHO classification of Tumours of endocrine organs. 4th ed. IARC: Lyon, France; 2017.
Maruta J, Hashimoto H, Suehisa Y, et al. Improving the diagnostic accuracy of thyroid follicular neoplasms: cytological features in fine-needle aspiration cytology. Diagn Cytopathol. 2011;39(1):28–34.
Somma J, Schlecht NF, Fink D, Khader SN, Smith RV, Cajigas A. Thyroid fine needle aspiration cytology: follicular lesions and the gray zone. Acta Cytol. 2010;54(2):123–31.
Bondeson L, Bondeson AG, Ljungberg O, Tibblin S. Oxyphil tumors of the thyroid: follow-up of 42 surgical cases. Ann Surg. 1981;194(6):677–80.
Schatz-Siemers N, Brandler TC, Oweity T, Sun W, Hernandez A, Levine P. Hürthle cell lesions on thyroid fine needle aspiration cytology: molecular and histologic correlation. Diagn Cytopathol. 2019 Oct;47(10):977–85.
Elliott DD, Pitman MB, Bloom L, Faquin WC. Fine-needle aspiration biopsy of Hurthle cell lesions of the thyroid gland: a cytomorphologic study of 139 cases with statistical analysis. Cancer. 2006 Apr 25;108(2):102–9.
Bishop JA, Ali SZ. Hyalinizing trabecular adenoma of the thyroid gland. Diagn Cytopathol. 2011;39(4):306–10.
Kuma S, Hirokawa M, Miyauchi A, Kakudo K, Katayama S. Cytologic features of hyalinizing trabecular adenoma of the thyroid. Acta Cytol. 2003;47(3):399–404.
Monappa V, Kudva R. Cytomorphologic diversity of papillary thyroid carcinoma. J Cytol. 2017 Oct-Dec;34(4):183–7.
Kaur A, Jayaram G. Thyroid tumors: cytomorphology of papillary carcinoma. Diagn Cytopathol. 1991;7(5):462–8.
Pusztaszeri M, Auger M. Update on the cytologic features of papillary thyroid carcinoma variants. Diagn Cytopathol. 2017 Aug;45(8):714–30.
Das DK, Mallik MK, Sharma P, et al. Papillary thyroid carcinoma and its variants in fine needle aspiration smears. A cytomorphologic study with special reference to tall cell variant. Acta Cytol. 2004;48(3):325–36.
Urano M, Kiriyama Y, Takakuwa Y, Kuroda M. Tall cell variant of papillary thyroid carcinoma: its characteristic features demonstrated by fine-needle aspiration cytology and immunohistochemical study. Diagn Cytopathol. 2009;37(10):732–7.
Suzuki A, Hirokawa M, Takada N, Higuchi M, Ito A, Yamao N, Hayashi T, Kuma S, Miyauchi A. Fine-needle aspiration cytology for medullary thyroid carcinoma: a single institutional experience in Japan. Endocr J. 2017 Nov 29;64(11):1099–104.
Bhanot P, Yang J, Schnadig VJ, Logrono R. Role of FNA cytology and immunochemistry in the diagnosis and management of medullary thyroid carcinoma: report of six cases and review of the literature. Diagn Cytopathol. 2007;35(5):285–92.
Zeppa P, Vetrani A, Marino M, et al. Fine needle aspiration cytology of medullary thyroid carcinoma: a review of 18 cases. Cytopathology. 1990;1(1):35–44.
Papaparaskeva K, Nagel H, Droese M. Cytologic diagnosis of medullary carcinoma of the thyroid gland. Diagn Cytopathol. 2000;22(6):351–8.
Barwad A, Dey P, Nahar Saikia U, Gupta N, Rajwanshi A, Nijhawan R, Srinivasan R. Fine needle aspiration cytology of insular carcinoma of thyroid. Diagn Cytopathol. 2012 May;40(Suppl 1):E43–7.
McIver B, Hay ID, Giuffrida DF, et al. Anaplastic thyroid carcinoma: a 50-year experience at a single institution. Surgery. 2001;130(6):1028–34.
Sangalli G, Serio G, Zampatti C, Lomuscio G, Colombo L. Fine needle aspiration cytology of primary lymphoma of the thyroid: a report of 17 cases. Cytopathology. 2001;12(4):257–63.
Babu N, Dey P. Fine needle aspiration cytology of non-Hodgkin’s lymphoma of thyroid. Cytopathology. 2002 Jun;13(3):188.
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Dey, P. (2021). Fine Needle Aspiration Cytology of Thyroid. In: Color Atlas of Fine Needle Aspiration Cytology. Springer, Singapore. https://doi.org/10.1007/978-981-15-8033-8_5
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DOI: https://doi.org/10.1007/978-981-15-8033-8_5
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