Abstract
Pediatric acute kidney injury is becoming a widely recognized clinical diagnosis that can be found across the clinical spectrum. The advances of genomic studies in the field of nephrology, specifically the pathophysiology mechanisms of ischemia-reperfusion, sepsis, and nephrotoxicity as they relate to acute kidney injury, have stimulated the desire to understand a genotype-phenotype connection. Ranging from targeted gene to genome-wide association studies, acute kidney injury genetic study designs warrant thoughtful methodology considerations in order to minimize bias and to improve result validity.
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Lee-Son, K., Attanasio, M. (2021). Genetic Influences on Pediatric AKI. In: Sethi, S.K., Raina, R., McCulloch, M., Bunchman, T.E. (eds) Advances in Critical Care Pediatric Nephrology. Springer, Singapore. https://doi.org/10.1007/978-981-33-4554-6_13
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DOI: https://doi.org/10.1007/978-981-33-4554-6_13
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