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Photoacoustic Tomography Opening New Paradigms in Biomedical Imaging

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Advanced Imaging and Bio Techniques for Convergence Science

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1310))

Abstract

After the emergence of the ultrasound, X-ray CT, PET, and MRI, photoacoustic tomography (PAT) is now in the phase of its exponential growth, with its expected full maturation being another form of mainstream clinical imaging modality. By combining the high contrast benefit of optical imaging and the high-resolution deep imaging capability of ultrasound, PAT can provide unprecedented anatomical image contrasts at clinically relevant depths as well as enable the use of a variety of functional and molecular imaging information, which is not possible with conventional imaging modalities. With these strengths, PAT has achieved numerous breakthroughs in various biomedical applications and also provided new technical platforms that may be able to resolve unmet issues in clinics. In this chapter, we provide an overview of the development of PAT technology for several major biomedical applications and provide an approximate projection of the future of PAT.

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Notes

  1. 1.

    This chapter is an opinionated review on the development and prospects of photoacoustic tomography with a view to pedagogical practicality. It has never meant to be comprehensive in scope or authoritative in any way. Rather, we start with fundamental concepts and principles underlying the state-of-the-art technologies, from which selected achievements are reviewed along the chronological progression of the field with an emphasis on the potential breakthrough innovations.

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Acknowledgments

This work was supported by the U-K Brand Research Fund (1.200032.01) of UNIST (Ulsan National Institute of Science and Technology) and Basic Science Research Program through the National Research Foundation (NRF) of Korea funded by the Ministry of Education (2015R1D1A1A01059361).

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Authors and Affiliations

  1. Center for Photoacoustic Medical Instruments, Department of Biomedical Engineering, Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea

    Joon-Mo Yang

  2. Department of Physics, School of Natural Science, Ulsan National Institute of Science and Technology, Ulsan, Republic of Korea

    Cheol-Min Ghim

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  1. Joon-Mo Yang
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  2. Cheol-Min Ghim
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Correspondence to Joon-Mo Yang .

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Editors and Affiliations

  1. Department of Convergence Medicine, University of Ulsan College of Medicine, Asan Institute for Life Sciences, Asan Medical Center, Seoul, Korea (Republic of)

    Jun Ki Kim

  2. Department of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea (Republic of)

    Jeong Kon Kim

  3. Department of Convergence Medicine, University of Ulsan College of Medicine, Asan Institute for Life Sciences, Asan Medical Center, Seoul, Korea (Republic of)

    Chan-Gi Pack

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Yang, JM., Ghim, CM. (2021). Photoacoustic Tomography Opening New Paradigms in Biomedical Imaging. In: Kim, J.K., Kim, J.K., Pack, CG. (eds) Advanced Imaging and Bio Techniques for Convergence Science. Advances in Experimental Medicine and Biology, vol 1310. Springer, Singapore. https://doi.org/10.1007/978-981-33-6064-8_11

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