1. Expression and integrity of DNA topoisomerase II isoforms does not explain generic drug resistance in malignant mesothelioma

   • Blair R. McLaren
   • Darrel Whitaker
   • Richard A. Lake

   Original Article Pages: 1 - 8

2. Plasmid expression of a peptide that selectively blocks oncogenic ras-p21-induced oocyte maturation

   • Cecilia Kovac
   • Lyndon Chie
   • Matthew R. Pincus

   Original Article Pages: 9 - 14

3. Pharmacological study of paclitaxel duration of infusion combined with GFR-based carboplatin in the treatment of ovarian cancer

   • Alan V. Boddy
   • Melanie J. Griffin
   • Hilary A. Calvert

   Original Article Pages: 15 - 21

4. Activity of high-dose toremifene plus cisplatin in platinum-treated non-small-cell lung cancer: a phase II California Cancer Consortium Trial

   • Primo N. Lara
   • David R. Gandara
   • James H. Doroshow

   Original Article Pages: 22 - 28

5. Structure-activity relationship studies of discodermolide and its semisynthetic acetylated analogs on microtubule function and cytotoxicity

   • Richard A. Isbrucker
   • Sarath P. Gunasekera
   • Ross E. Longley

   Original Article Pages: 29 - 36

6. Fendiline, an anti-anginal drug, increases intracellular Ca²⁺ in PC3 human prostate cancer cells

   • C. Jan
   • K. Lee
   • J. Huang

   Original Article Pages: 37 - 41

7. Induction of cytochrome P450 3A4 by docetaxel in peripheral mononuclear cells and its expression in lung cancer

   • Kazunori Fujitaka
   • Tetsuya Oguri
   • Nobuoki Kohno

   Original Article Pages: 42 - 46

8. Acyl derivatives of demethylpenclomedine, an antitumor-active, non-neurotoxic metabolite of penclomedine

   • Robert F. Struck
   • Anita Tiwari
   • William R. Waud

   Original Article Pages: 47 - 52

9. Population pharmacokinetics of ifosfamide and its 2- and 3-dechloroethylated and 4-hydroxylated metabolites in resistant small-cell lung cancer patients

   • Thomas Kerbusch
   • John W. van Putten
   • Jos H. Beijnen

   Original Article Pages: 53 - 61

10. Markedly diminished drug resistance-inducing properties of vinflunine (20′,20′-difluoro-3′,4′-dihydrovinorelbine) relative to vinorelbine, identified in murine and human tumour cells in vivo and in vitro

    • Chantal Etiévant
    • Anna Kruczynski
    • Bridget T. Hill

    Original Article Pages: 62 - 70

11. Antineoplastic action of 5-aza-2′-deoxycytidine and histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor β and estrogen receptor α genes in breast carcinoma cells

    • Veronica Bovenzi
    • Richard L. Momparler

    Original Article Pages: 71 - 76

12. Pharmacokinetics of Erwinia asparaginase after intravenous and intramuscular administration

    • Birgitte Albertsen
    • Preben Jakobsen
    • Niels T. Carlsen

    Original Article Pages: 77 - 82

13. Therapeutic activity of 7-[(2-trimethylsilyl)ethyl)]-20 (S)-camptothecin against central nervous system tumor-derived xenografts in athymic mice

    • Stephen T. Keir
    • Frederick Hausheer
    • Henry S. Friedman

    Original Article Pages: 83 - 87

14. Combination chemotherapy with ifosfamide, 5-fluorouracil, etoposide and cisplatin for metastatic urothelial cancer

    • Iwao Fukui
    • Junji Yonese
    • Daisuke Ishiwata

    Original Article Pages: 88 - 93