1. Introduction

   • H. C. Thomas

   EditorialNotes Pages: 395 - 396

2. The nature of the hepatitis B virus and its mode of replication

   • C. R. Howard

   OriginalPaper Pages: 397 - 419

3. The immunopathology of acute type B hepatitis

   • Leonardo Bianchi

   OriginalPaper Pages: 421 - 438

4. Theimunopathogenesis of cronic HBV inducedliver disease

   • Gary A. Levy
   • Francis V. Chisari

   OriginalPaper Pages: 439 - 459

5. Immunopathogenesis of the extrahepatic manifestations of hepatitis B virus infection

   • Jules L. Dienstag

   OriginalPaper Pages: 461 - 472

6. Primary liver cancer and its relationship to chronic infection with the hepatitis B virus

   • Stephanos J. Hadziyannis

   OriginalPaper Pages: 473 - 485