1. Genotype and phenotype in patients with dihydropyrimidine dehydrogenase deficiency

   • A. B. P. Van Kuilenburg
   • P. Vreken
   • A. H. Van Gennip

   Review article Pages: 1 - 9

2. Werner syndrome lymphoblastoid cells are sensitive to camptothecin-induced apoptosis in S-phase

   • M. Poot
   • Katherine A. Gollahon
   • Peter S. Rabinovitch

   Rapid commmunication Pages: 10 - 14

3. Disentangling the perturbational effects of amino acid substitutions in the DNA-binding domain of p53

   • A. I. Wacey
   • D. N. Cooper
   • M. Krawczak

   Original investigation Pages: 15 - 22

4. A trisomic germ cell line and precocious chromatid segregation leads to recurrent trisomy 21 conception

   • J. Cozzi
   • Clare M. Conn
   • J. D. A. Delhanty

   Original investigation Pages: 23 - 28

5. A rapid automated SSCP multiplex capillary electrophoresis protocol that detects the two common mutations implicated in hereditary hemochromatosis (HH)

   • H. M. Wenz
   • Susanne Baumhueter
   • Mark Worwood

   Original investigation Pages: 29 - 35

6. A G to A transition at the last nucleotide of exon 6 of the γc gene (868G→A) may result in either a splice or missense mutation in patients with X-linked severe combined immunodeficiency

   • Nobuko Kanai
   • Fumio Yanai
   • Akihisa Mitsudome

   Original investigation Pages: 36 - 42

7. Xp deletions associated with autism in three females

   • N. S. Thomas
   • Andrew J. Sharp
   • Nicholas R. Dennis

   Original investigation Pages: 43 - 48

8. A new assay for the analysis of X-chromosome inactivation based on methylation-specific PCR

   • T. Kubota
   • Shigeaki Nonoyama
   • Yoshimitsu Fukushima

   Original investigation Pages: 49 - 55

9. Fibroblast growth factor homologous factor 2 (FHF2): gene structure, expression and mapping to the Börjeson-Forssman-Lehmann syndrome region in Xq26 delineated by a duplication breakpoint in a BFLS-like patient

   • J. Gecz
   • Elizabeth Baker
   • John C. Mulley

   Original investigation Pages: 56 - 63

10. Delineation of two distinct 6p deletion syndromes

    • Angela F. Davies
    • Ghazala Mirza
    • J. Ragoussis

    Original investigation Pages: 64 - 72

11. Refined mapping of the gene for autosomal dominant retinitis pigmentosa (RP17) on chromosome 17q22

    • A. I. den Hollander
    • S. D. van der Velde-Visser
    • Frans P. M. Cremers

    Original investigation Pages: 73 - 76

12. Refined genetic and physical positioning of the gene for Doyne honeycomb retinal dystrophy (DHRD)

    • Sana Kermani
    • Kevin Gregory-Evans
    • C. Y. Gregory-Evans

    Original investigation Pages: 77 - 82

13. P57 (KIP2) polymorphisms and breast cancer risk

    • Y. Li
    • R. C. Millikan
    • E. T. Li

    Original investigation Pages: 83 - 88

14. Genotyping single nucleotide polymorphisms by primer extension and high performance liquid chromatography

    • Bastiaan Hoogendoorn
    • Michael J. Owen
    • M. C. O’Donovan

    Original investigation Pages: 89 - 93

15. A large Alu-mediated deletion, identified by PCR, as the molecular basis for glycogen storage disease Type II (GSDII)

    • M. L. Huie
    • A. L. Shanske
    • R. Hirschhorn

    Original investigation Pages: 94 - 98

16. Mapping and genomic characterization of the gene encoding diacylglycerol kinase γ (DAGK3): assessment of its role in dominant optic atrophy (OPA1)

    • Heidi Stöhr
    • Jörg Klein
    • B. H. F. Weber

    Original investigation Pages: 99 - 105

17. Characterization of a novel α-mannosidosis-causing mutation and its use in leukocyte genotyping after bone marrow transplantation

    • H. M. Frostad Riise
    • Gaute Martin Hansen
    • Øivind Nilssen

    Short report Pages: 106 - 107

18. Exclusion of the Sonic Hedgehog gene as responsible for Currarino syndrome and anorectal malformations with sacral hypodevelopment

    • M. Seri
    • Giuseppe Martucciello
    • Vincenzo Jasonni

    Short report Pages: 108 - 110

19. Letter to the editor

    • Y. T. Chen

    Pages: 111 - 111

20. Glycogen storage disease III subtypes and muscle weakness during childhood

    • M. Okubo
    • A. Horinishi
    • T. Murase

    Reply Pages: 112 - 112

21. Erratum: Hum Genet (1998) 103:666–673

    Pages: 113 - 113