Abstract
A standardized nomenclature is critical for the accurate and consistent description of genomic changes as identified by karyotyping, fluorescence in situ hybridization and microarray. The International System for Human Cytogenomic Nomenclature (ISCN) is the central reference for the description of karyotyping, FISH, and microarray results, and provides rules for describing cytogenetic and molecular cytogenetic findings in laboratory reports. These laboratory reports are documents to the referring clinician, and should be clear, accurate and contain all information relevant for good interpretation of the cytogenetic findings. Here, we describe guidelines for cytogenetic nomenclature and laboratory reports for cytogenetic testing applied to tumor samples.
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Stevens-Kroef, M., Simons, A., Rack, K., Hastings, R.J. (2017). Cytogenetic Nomenclature and Reporting. In: Wan, T. (eds) Cancer Cytogenetics. Methods in Molecular Biology, vol 1541. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6703-2_24
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DOI: https://doi.org/10.1007/978-1-4939-6703-2_24
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Publisher Name: Humana Press, New York, NY
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Online ISBN: 978-1-4939-6703-2
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