Abstract
Inflammation is a common symptom of inflammatory bowel disease (IBD). Actually, many experimental models of colitis exist and try to mimic the human situation in order to understand the pathogenesis of Crohn’s disease and ulcerative colitis. These experimental models of inflammation can be characterized by specific parameters, which illustrate the proceeding inflammatory process. By use of these models potentially new reagents for improved therapeutic approaches can be analyzed. Here, we describe the TNBS-mediated colitis model and specify different parameters for the detailed characterization of the inflammatory process in experimental colitis models.
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Acknowledgment
B.W. was supported by DFG grants WE4656/2-2 and SFB 1181-B02.
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Reißig, S., Weigmann, B. (2017). Monitoring of Chemically Induced Colitis. In: Clausen, B., Laman, J. (eds) Inflammation. Methods in Molecular Biology, vol 1559. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-6786-5_20
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DOI: https://doi.org/10.1007/978-1-4939-6786-5_20
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Publisher Name: Humana Press, New York, NY
Print ISBN: 978-1-4939-6784-1
Online ISBN: 978-1-4939-6786-5
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