Abstract
Quantitative approaches in proteomics are emerging as a powerful tool to probe the dynamics of protein expression across biological conditions. Thereby, quantification helps to recognize proteins with potential biological relevance, which greatly aids in the design of follow-up experiments. Although multiple methods have been established that are based on stable-isotope labeling and label-free approaches, one of the remaining bottlenecks is the analysis and quantification of proteins in large datasets. MSQuant is a platform for protein quantification, capable of handling multiple labeling strategies and supporting several vendor data formats. Here, we report on the use and versatility of MSQuant.
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Gouw, J.W., Krijgsveld, J. (2012). MSQuant: A Platform for Stable Isotope-Based Quantitative Proteomics. In: Marcus, K. (eds) Quantitative Methods in Proteomics. Methods in Molecular Biology, vol 893. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61779-885-6_31
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DOI: https://doi.org/10.1007/978-1-61779-885-6_31
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Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-61779-884-9
Online ISBN: 978-1-61779-885-6
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