Abstract
Optical coherence tomography (OCT) is an invaluable technique to perform noninvasive retinal imaging in small animal models such as mice. It provides virtual cross sections that correlate well with histomorphometric data with the advantage that multiple iterative measurements can be acquired in time line analyses to detect dynamic changes and reduce the amount of animals needed per study.
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Acknowledgements
The authors wish to acknowledge the continued support and mentoring by Drs. Zrenner, Bartz-Schmidt, Ueffing, and MacLaren.
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Fischer, M.D., Zhour, A., Kernstock, C.J. (2012). Phenotyping of Mouse Models with OCT. In: Weber, B., LANGMANN, T. (eds) Retinal Degeneration. Methods in Molecular Biology, vol 935. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-080-9_5
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DOI: https://doi.org/10.1007/978-1-62703-080-9_5
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Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-62703-079-3
Online ISBN: 978-1-62703-080-9
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