Abstract
Electrophysiological recordings from an acutely sliced preparation provide information on ionic currents and excitability of native neurons under near physiological conditions. Although this technique is commonly used on central nervous system structures such as spinal cord and brain, structures within the peripheral nervous system (including sensory ganglia and fibers) have proven to be much more difficult to study in acute preparations. Here we describe a method for patch-clamp recordings from rat dorsal root ganglion (DRG) slices.
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Acknowledgments
This work was supported by the MRC, BBSRC, and Wellcome Trust.
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Rose, K.E., Gigout, S., Gamper, N. (2013). M-Current Recording from Acute DRG Slices. In: Gamper, N. (eds) Ion Channels. Methods in Molecular Biology, vol 998. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-351-0_25
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DOI: https://doi.org/10.1007/978-1-62703-351-0_25
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Publisher Name: Humana Press, Totowa, NJ
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Online ISBN: 978-1-62703-351-0
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