Abstract
Mosquito injection of Plasmodium sporozoites into the bloodstream is followed by a short transit period before invasion of the hepatocyte, the only host cell expressing class I major histocompatibility complex (MHC) molecules. Liver stages develop within the hepatocyte for periods that vary according to the species, and they express various stage-specific proteins. Finally, schizonts are released into the bloodstream and invade the red blood cells, the final host cell before the continuation of the parasite cycle upon a subsequent mosquito bite.
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Peter, K., Audran, R., Bonelo, A., Corradin, G., López, J.A. (2002). Assessment of Antigen-Specific CTL- and CD8+-Dependent IFN-γ Responses in Mice. In: Doolan, D.L. (eds) Malaria Methods and Protocols. Methods in Molecular Medicine™, vol 72. Humana Press. https://doi.org/10.1385/1-59259-271-6:437
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DOI: https://doi.org/10.1385/1-59259-271-6:437
Publisher Name: Humana Press
Print ISBN: 978-0-89603-823-3
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