Antigen-dependent T cell/B cell activation requires costimulatory signals. Immune deficiencies have shown that the interaction between CD40 on the B cell surface and CD40 ligand on the T cell surface is essential for the initiation of a germinal centre reaction. CD40 belongs to the family of tumor necrosis factor-like receptors.
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© 2005 Springer-Verlag
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(2005). CD40 Ligand. In: Vohr, HW. (eds) Encyclopedic Reference of Immunotoxicology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27806-0_224
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DOI: https://doi.org/10.1007/3-540-27806-0_224
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-44172-4
Online ISBN: 978-3-540-27806-1
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