The product of nuclear transplantation when an enucleated egg is combined with an isolated nucleus from a somatic cell. The term is coined from the analogy of a zygote that is the product of the natural fertilization of an egg by a sperm. Production of a clonote would be, in all essential ways, reproductive cloning. A clonote could also be exploited for stem cell research but it appears inadvisable to use it for human reproduction on both ethical and biological grounds. in vitro fertilization, nuclear transplantation, stem cells; McHugh PR 2004 New England J Med 351:209.
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(2008). Clonote. In: Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-6754-9_3174
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DOI: https://doi.org/10.1007/978-1-4020-6754-9_3174
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