Skip to main content

Ambulatory Blood Pressure Monitoring Methodology and Norms in Children

  • Reference work entry
  • First Online:
Pediatric Hypertension
  • 738 Accesses

Abstract

Over the last decades, ambulatory blood pressure monitoring (ABPM) has become the method of choice for the diagnosis and therapeutic monitoring of arterial hypertension in adult and pediatric patients. ABPM allows a more representative observation of blood pressure throughout day and night in a nonmedical environment compared with office blood pressure measurements and allows for an assessment of the circadian and even ultradian blood pressure variability. ABPM provides the ability to detect white coat and masked hypertension, better reproducibility of measurements and superior prediction of target organ damage. The use, interpretation, and limitations of ABPM in children and adolescents will be discussed in this chapter.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

Abbreviations

ABPM:

Ambulatory blood pressure monitoring

BP:

Blood pressure

cIMT:

Carotid intima-media thickness

CKD:

Chronic kidney disease

CV:

Cardiovascular

CVD:

Cardiovascular disease

DBP:

Diastolic blood pressure

HBP:

Home blood pressure measurement

LVH:

Left ventricular hypertrophy

LVM:

Left ventricular mass

MAP:

Mean arterial blood pressure

MH:

Masked hypertension

OBP:

Office (or casual) blood pressure measurement

SBP:

Systolic blood pressure

TOD:

Target organ damage

WCH:

White coat hypertension

References

  • Abdalla M, Goldsmith J, Muntner P, Diaz KM, Reynolds K, Schwartz JE, Shimbo D (2016) Is isolated nocturnal hypertension a reproducible phenotype? Am J Hypertens 29(1):33–38

    Article  Google Scholar 

  • Bo Y, Kwok KO, Chung VC, Yu CP, Tsoi KK, Wong SY, Lee EK (2020) Short-term reproducibility of ambulatory blood pressure measurements: a systematic review and meta-analysis of 35 observational studies. J Hypertens 38(11):2095–2109

    Article  CAS  Google Scholar 

  • Cole TJ, Green PJ (1992) Smoothing reference centile curves: the LMS method and penalized likelihood. StatMed 11:1305–1319

    CAS  Google Scholar 

  • Cuspidi C, Meani S, Valerio C, Sala C, Fusi V, Masaidi M, Zanchetti A, Mancia G (2007) Reproducibility of dipping/nondipping pattern in untreated essential hypertensive patients: impact of sex and age. Blood Press Monit 12(2):101–106

    Article  Google Scholar 

  • Davis ML, Ferguson MA, Zachariah JP (2014) Clinical predictors and impact of ambulatory blood pressure monitoring in pediatric hypertension referrals. J Am Soc Hypertens 8(9):660–667

    Article  Google Scholar 

  • de la Sierra A, Vinyoles E, Banegas JR, Parati G, de la Cruz JJ, Gorostidi M, Segura J, Ruilope LM (2016) Short-term and long-term reproducibility of hypertension phenotypes obtained by office and ambulatory blood pressure measurements. J Clin Hypertens (Greenwich) 18(9):927–933

    Article  Google Scholar 

  • de Man SA, André JL, Bachmann HJ, Grobbee DE, Ibsen KK, Laaser U, Lippert P, Hofmann A (1991) Blood pressure in childhood: pooled findings of six European studies. J Hypertens 9:109–114

    Article  Google Scholar 

  • Duzova A, Karabay Bayazit A, Canpolat N, Niemirska A, Kaplan Bulut I, Azukaitis K, Karagoz T, Oguz B, Erdem S, Anarat A, Ranchin B, Shroff R, Djukic M, Harambat J, Yilmaz A, Yildiz N, Ozcakar B, Buscher A, Lugani F, Wygoda S, Tschumi S, Zaloszyc A, Jankauskiene A, Laube G, Galiano M, Kirchner M, Querfeld U, Melk A, Schaefer F, Wühl E, 4C Study Consortium (2019) Isolated nocturnal and isolated daytime hypertension associate with altered cardiovascular morphology and function in children with chronic kidney disease: findings from the cardiovascular comorbidity in children with chronic kidney disease study. J Hypertens 37(11):2247–2255

    Article  Google Scholar 

  • El Mokadem M, Boshra H, Abd El Hady Y, Kasla A, Gouda A (2020) Correlation between blood pressure variability and subclinical target organ damage in patients with essential hypertension. J Hum Hypertens 34(9):641–647

    Article  Google Scholar 

  • Ettinger LM, Freeman K, DiMartino-Nardi JR, Flynn JT (2005) Microalbuminuria and abnormal ambulatory blood pressure in adolescents with type 2 diabetes mellitus. J Pediatr 147:67–73

    Article  CAS  Google Scholar 

  • Flechtner-Mors M, Neuhauser H, Reinehr T, Roost HP, Wiegand S, Siegfried W, Zwiauer K, Molz E, Holl RW, APV Initiative and the BMBF Competence Network Obesity (2015) Blood pressure in 57,915 pediatric patients who are overweight or obese based on five reference systems. Am J Cardiol 115(11):1587–1594

    Article  Google Scholar 

  • Flynn JT (2011) Ambulatory blood pressure monitoring in children: imperfect yet essential. Pediatr Nephrol 26(12):2089–2094

    Article  Google Scholar 

  • Flynn JT, Daniels SR, Hayman LL, Maahs DM, McCrindle BW, Mitsnefes M, Zachariah JP, Urbina EM, American Heart Association Atherosclerosis, Hypertension and Obesity in Youth Committee of the Council on Cardiovascular Disease in the Young (2014) Update: ambulatory blood pressure monitoring in children and adolescents: a scientific statement from the American Heart Association. Hypertension 63(5):1116–1135

    Article  CAS  Google Scholar 

  • Flynn JT, Kaelber DC, Baker-Smith CM, Blowey D, Carroll AE, Daniels SR, de Ferranti SD, Dionne JM, Falkner B, Flinn SK, Gidding SS, Goodwin C, Leu MG, Powers ME, Rea C, Samuels J, Simasek M, Thaker VV, Urbina EM, Subcommittee on Screening and Management of High Blood Pressure in Children (2017) Clinical practice guideline for screening and management of high blood pressure in children and adolescents. Pediatrics 140(3):e20171904

    Article  Google Scholar 

  • Flynn JT, Urbina EM, Brady TM, Baker-Smith C, Daniels SR, Hayman LL, Mitsnefes M, Tran A, Zachariah JP, on behalf of the Atherosclerosis, Hypertension and Obesity in Youth Committee of the American Heart Association, Council on Lifelong Congenital Heart Disease and Heart Health in the Young, Council on Cardiovascular Radiology and Intervention, Council on Epidemiology and Prevention, Council on Hypertension and Council on Lifestyle and Cardiometabolic Health (2022). Ambulatory Blood Pressure Monitoring in Children and Adolescents: 2021 Update: a scientific statement from the American Heart Association. Hypertension 79(7):e114–e124. https://doi.org/10.1161/HYP.0000000000000215. Epub 2022 May 23

  • Fujita H, Matsuoka S, Awazu M (2018) Masked isolated nocturnal hypertension in children and young adults. Pediatr Cardiol 39(1):66–70

    Article  Google Scholar 

  • Gartlehner G, Vander Schaaf EB, Orr C, Kennedy SM, Clark R, Viswanathan M (2020) Screening for hypertension in children and adolescents: updated evidence report and systematic review for the US preventive services task force. JAMA 324(18):1884–1895

    Article  Google Scholar 

  • Gellermann J, Kraft S, Ehrich JH (1997) Twenty-four-hour ambulatory blood pressure monitoring in young children. Pediatr Nephrol 11(6):707–710

    Article  CAS  Google Scholar 

  • Gimpel C, Wühl E, Arbeiter K, Drozdz D, Trivelli A, Charbit M, Gellermann J, Dusek J, Jankauskiene A, Emre S, Schaefer F, Escape Trial Group (2009) Superior consistency of ambulatory blood pressure monitoring in children: implications for clinical trials. J Hypertens 27(8):1568–1574

    Article  CAS  Google Scholar 

  • Hadtstein C, Wühl E, Soergel M, Witte K, Schaefer F (2004) Normative values for circadian and ultradian cardiovascular rhythms in childhood. Hypertension 43(3):547–554

    Article  CAS  Google Scholar 

  • Halbach S (2020) Practical application of ABPM in the pediatric nephrology clinic. Pediatr Nephrol 35(11):2067–2076

    Article  Google Scholar 

  • Hamdani G, Flynn JT, Daniels S, Falkner B, Hanevold C, Ingelfinger J, Lande MB, Martin LJ, Meyers KE, Mitsnefes M, Rosner B, Samuels J, Urbina EM (2019) Ambulatory blood pressure monitoring tolerability and blood pressure status in adolescents: the SHIP AHOY study. Blood Press Monit 24(1):12–17

    Article  Google Scholar 

  • Hamdani G, Mitsnefes MM, Flynn JT, Becker RC, Daniels S, Falkner BE, Ferguson M, Hooper SR, Hanevold CD, Ingelfinger JR, Lande M, Martin LJ, Meyers KE, Rosner B, Samuels J, Urbina EM (2021) Pediatric and adult ambulatory blood pressure thresholds and blood pressure load as predictors of left ventricular hypertrophy in adolescents. Hypertension 78(1):30–37

    Article  CAS  Google Scholar 

  • Harshfield GA, Alpert BS, Pulliam DA, Somes GW, Wilson DK (1994) Ambulatory blood pressure recordings in children and adolescents. Pediatrics 94(2):180–184

    Article  CAS  Google Scholar 

  • Haskin O, Wong CJ, McCabe L, Begin B, Sutherland SM, Chaudhuri A (2015) 44-h ambulatory blood pressure monitoring: revealing the true burden of hypertension in pediatric hemodialysis patients. Pediatr Nephrol 30(4):653–660

    Article  Google Scholar 

  • King-Schultz L, Weaver AL, Cramer CH (2012) Correlation of blood pressure readings from 6-hour intervals with the daytime period of 24-hour ambulatory blood pressure monitoring in pediatric patients. J Clin Hypertens (Greenwich) 14(6):396–400

    Article  Google Scholar 

  • Krmar RT (2019) White-coat hypertension from a paediatric perspective. Acta Paediatr 108(1):44–49

    Article  Google Scholar 

  • Lee J, McCulloch CE, Flynn JT, Samuels J, Warady BA, Furth SL, Seth D, Grimes BA, Mitsnefes MM, Ku E (2020) Prognostic value of ambulatory blood pressure load in pediatric CKD. Clin J Am Soc Nephrol 15(4):493–500

    Article  CAS  Google Scholar 

  • Li Y, Thijs L, Boggia J, Asayama K, Hansen TW, Kikuya M, Bjorklund-Bodegard K, Ohkubo T, Jeppesen J, Torp-Pedersen C, Dolan E, Kuznetsova T, Stolarz-Skrzypek K, Tikhonoff V, Malyutina S, Casiglia E, Nikitin Y, Lind L, Sandoya E, Kawecka-Jaszcz K, Filipovsky J, Imai Y, Ibsen H, O’Brien E, Wang J, Staessen JA, International Database on Ambulatory Blood Pressure in relation to Cardiovascular Outcomes (IDACO) Investigators (2014) Blood pressure load does not add to ambulatory blood pressure level for cardiovascular risk stratification. Hypertension 63(5):925–933

    Article  CAS  Google Scholar 

  • Litwin M, Simonetti GD, Niemirska A, Ruzicka M, Wühl E, Schaefer F, Feber J (2010) Altered cardiovascular rhythmicity in children with white coat and ambulatory hypertension. Pediatr Res 67(4):419–423

    Article  Google Scholar 

  • Liu M, Takahashi H, Morita Y, Maruyama S, Mizuno M, Yuzawa Y, Watanabe M, Toriyama T, Kawahara H, Matsuo S (2003) Non-dipping is a potent predictor of cardiovascular mortality and is associated with autonomic dysfunction in haemodialysis patients. Nephrol Dial Transplant 18:563–569

    Article  Google Scholar 

  • Lubrano R, Paoli S, Spiga S, Falsaperla R, Vitaliti G, Gentile I, Elli M (2015) Impact of ambulatory blood pressure monitoring on the diagnosis of hypertension in children. J Am Soc Hypertens 9(10):780–784

    Article  Google Scholar 

  • Lurbe E, Redon J, Liao Y, Tacons J, Cooper RS, Alvarez V (1994) Ambulatory blood pressure monitoring in normotensive children. J Hypertens 12:1417–1423

    Article  CAS  Google Scholar 

  • Lurbe E, Redon J, Kesani A, Pascual JM, Tacons J, Alvarez V, Batlle D (2002) Increase in nocturnal blood pressure and progression to microalbuminuria in type 1 diabetes. N Engl J Med 347:797–805

    Article  CAS  Google Scholar 

  • Lurbe E, Torro I, Alvarez V, Nawrot T, Paya R, Redon J, Staessen J (2005) Prevalence, persistence and clinical significance of masked hypertension in youth. Hypertension 45:493–398

    Article  CAS  Google Scholar 

  • Lurbe E, Agabiti-Rosei E, Cruickshank JK, Dominiczak A, Erdine S, Hirth A, Invitti C, Litwin M, Mancia G, Pall D, Rascher W, Redon J, Schaefer F, Seeman T, Sinha M, Stabouli S, Webb NJ, Wühl E, Zanchetti A (2016) 2016 European Society of Hypertension guidelines for the management of high blood pressure in children and adolescents. J Hypertens 34(10):1887–1920

    Article  CAS  Google Scholar 

  • Macumber I (2017) Ambulatory blood pressure monitoring in children and adolescents: a review of recent literature and new guidelines. Curr Hypertens Rep 19(12):96

    Article  Google Scholar 

  • Menghetti E, Virdis R, Strambi M, Patriarca V, Riccioni MA, Fossali E, Spagnolo A (1999) Blood pressure in childhood and adolescents: the Italian normal standards. J Hypertens 17:1363–1372

    Article  CAS  Google Scholar 

  • Mitsnefes M, Flynn J, Cohn S, Samuels J, Blydt-Hansen T, Saland J, Kimball T, Furth S, Warady B (2010) Masked hypertension associates with left ventricular hypertrophy in children with CKD. J Am Soc Nephrol 21:137–144

    Article  CAS  Google Scholar 

  • Mitsnefes MM, Pierce C, Flynn J, Samuels J, Dionne J, Furth S, Warady B, CKiD Study Group (2016) Can office blood pressure readings predict masked hypertension? Pediatr Nephrol 31(1):163–166

    Article  Google Scholar 

  • Mitsnefes M, Flynn JT, Brady T, Baker-Smith C, Daniels SR, Hayman LL, Tran A, Zachariah JP, Urbina EM (2021) Pediatric ambulatory blood pressure classification: the case for a change. Hypertension 78(5):1206–1210

    Article  CAS  Google Scholar 

  • National High Blood Pressure Education Program Working Group on High Blood Pressure in Children and Adolescents (2004) The fourth report on the diagnosis, evaluation, and treatment of high blood pressure in children and adolescents. Pediatrics 114:555–576

    Article  Google Scholar 

  • Niiranen TJ, Lindroos A, Johansson J, Puukka P, Kantola I (2016) Nighttime blood pressure measured with a timer-equipped home device – an alternative to nighttime ambulatory monitoring. J Am Soc Hypertens 10 Suppl 1:e2

    Article  CAS  Google Scholar 

  • O’Brien E, Parati G, Stergiou G, Asmar R, Beilin L, Bilo G, Clement D, de la Sierra A, de Leeuw P, Dolan E, Fagard R, Graves J, Head GA, Imai Y, Kario K, Lurbe E, Mallion JM, Mancia G, Mengden T, Myers M, Ogedegbe G, Ohkubo T, Omboni S, Palatini P, Redon J, Ruilope LM, Shennan A, Staessen JA, vanMontfrans G, Verdecchia P, Waeber B, Wang J, Zanchetti A, Zhang Y, European Society of Hypertension Working Group on Blood Pressure Monitoring (2013) European Society of Hypertension position paper on ambulatory blood pressure monitoring. J Hypertens 31(9):1731–1768

    Article  Google Scholar 

  • O’Flynn AM, Madden JM, Russell AJ, Curtin RJ, Kearney PM (2015) Isolated nocturnal hypertension and subclinical target organ damage: a systematic review of the literature. Hypertens Res 38(8):570–575

    Article  Google Scholar 

  • O’Sullivan JJ, Derrick G, Griggs P, Foxall R, Aitkin M, Wren C (1999) Ambulatory blood pressure in schoolchildren. Arch Dis Child 80:529–532

    Article  Google Scholar 

  • Obrycki L, Feber J, Derezinski T, Lewandowska W, Kulaga Z, Litwin M (2020) Hemodynamic patterns and target organ damage in adolescents with ambulatory prehypertension. Hypertension 75(3):826–834

    Article  CAS  Google Scholar 

  • Ohkubo T, Hozawa A, Yamaguchi J, Kikuya M, Ohmori K, Michima M, Matsubara M, Hashimoto J, Hoshi H, Araki T, Tsuji I, Satoh H, Hisamichi S, Imai Y (2002) Prognostic significance of the nocturnal decline in blood pressure in individuals with and without high 24-h blood pressure: the Ohasama study. J Hypertens 20(11):2183–2189

    Article  CAS  Google Scholar 

  • Parati G, Stergiou G, O’Brien E, Asmar R, Beilin L, Bilo G, Clement D, de la Sierra A, de Leeuw P, Dolan E, Fagard R, Graves J, Head GA, Imai Y, Kario K, Lurbe E, Mallion JM, Mancia G, Mengden T, Myers M, Ogedegbe G, Ohkubo T, Omboni S, Palatini P, Redon J, Ruilope LM, Shennan A, Staessen JA, vanMontfrans G, Verdecchia P, Waeber B, Wang J, Zanchetti A, Zhang Y, European Society of Hypertension Working Group on Blood Pressure Monitoring and Cardiovascular Variability (2014) European Society of Hypertension practice guidelines for ambulatory blood pressure monitoring. J Hypertens 32(7):1359–1366

    Article  CAS  Google Scholar 

  • Park MK, Menard SW, Yuang C (2001) Comparison of auscultatory and oscillometric blood pressures. Arch Pediatr Adolesc Med 155:50–53

    Article  CAS  Google Scholar 

  • Portman RJ, Yetman RJ, West MS (1991) Efficacy of 24-hour ambulatory blood pressure monitoring in children. J Pediatr 118:842–849

    Article  CAS  Google Scholar 

  • Rabi DM, McBrien KA, Sapir-Pichhadze R, Nakhla M, Ahmed SB, Dumanski SM, Butalia S, Leung AA, Harris KC, Cloutier L, Zarnke KB, Ruzicka M, Hiremath S, Feldman RD, Tobe SW, Campbell TS, Bacon SL, Nerenberg KA, Dresser GK, Fournier A, Burgess E, Lindsay P, Rabkin SW, Prebtani APH, Grover S, Honos G, Alfonsi JE, Arcand J, Audibert F, Benoit G, Bittman J, Bolli P, Cote AM, Dionne J, Don-Wauchope A, Edwards C, Firoz T, Gabor JY, Gilbert RE, Gregoire JC, Gryn SE, Gupta M, Hannah-Shmouni F, Hegele RA, Herman RJ, Hill MD, Howlett JG, Hundemer GL, Jones C, Kaczorowski J, Khan NA, Kuyper LM, Lamarre-Cliche M, Lavoie KL, Leiter LA, Lewanczuk R, Logan AG, Magee LA, Mangat BK, McFarlane PA, McLean D, Michaud A, Milot A, Moe GW, Penner SB, Pipe A, Poppe AY, Rey E, Roerecke M, Schiffrin EL, Selby P, Sharma M, Shoamanesh A, Sivapalan P, Townsend RR, Tran K, Trudeau L, Tsuyuki RT, Vallee M, Woo V, Bell AD, Daskalopoulou SS (2020) Hypertension Canada’s 2020 comprehensive guidelines for the prevention, diagnosis, risk assessment, and treatment of hypertension in adults and children. Can J Cardiol 36(5):596–624

    Article  Google Scholar 

  • Reichert H, Lindinger A, Frey O, Mortzeck J, Kiefer J, Busch C, Hoffmann W (1995) Ambulatory blood pressure monitoring in healthy schoolchildren. Pediatr Nephrol 9:282–286

    Article  CAS  Google Scholar 

  • Rosner B, Cook NR, Daniels S, Falkner B (2013) Childhood blood pressure trends and risk factors for high blood pressure: the NHANES experience 1988–2008. Hypertension 62(2):247–254

    Article  CAS  Google Scholar 

  • Samuels J, Ng D, Flynn JT, Mitsnefes M, Poffenbarger T, Warady BA, Furth S, Chronic Kidney Disease in Children Study Group (2012) Ambulatory blood pressure patterns in children with chronic kidney disease. Hypertension 60(1):43–50

    Article  CAS  Google Scholar 

  • Saner C, Simonetti GD, Wühl E, Mullis PE, Janner M (2016) Circadian and ultradian cardiovascular rhythmicity in obese children. Eur J Pediatr 175(8):1031–1038

    Article  CAS  Google Scholar 

  • Schaefer F, Doyon A, Azukaitis K, Bayazit A, Canpolat N, Duzova A, Niemirska A, Sozeri B, Thurn D, Anarat A, Ranchin B, Litwin M, Caliskan S, Candan C, Baskin E, Yilmaz E, Mir S, Kirchner M, Sander A, Haffner D, Melk A, Wühl E, Shroff R, Querfeld U, 4C Study Consortium (2017) Cardiovascular phenotypes in children with CKD: the 4C study. Clin J Am Soc Nephrol 12(1):19–28

    Article  Google Scholar 

  • Siven SS, Niiranen TJ, Kantola IM, Jula AM (2016) White-coat and masked hypertension as risk factors for progression to sustained hypertension: the Finn-Home study. J Hypertens 34(1):54–60

    Article  CAS  Google Scholar 

  • Soergel M, Kirschstein M, Busch C, Danne T, Gellermann J, Holl R, Krull F, Reichert H, Reusz GS, Rascher W (1997) Oscillometric twenty-four-hour ambulatory blood pressure values in healthy children and adolescents: a multicenter trial including 1141 subjects. J Pediatr 130:178–184

    Article  CAS  Google Scholar 

  • Sorof JM, Poffenbarger T, Franco K, Portman R (2001) Evaluation of white coat hypertension in children: importance of the definitions of normal ambulatory blood pressure and the severity of casual hypertension. Am J Hypertens 14:855–860

    Article  CAS  Google Scholar 

  • Stabouli S, Kotsis V, Toumanidis S, Papamichael C, Constantopoulos A, Zakopoulos N (2005) White-coat and masked hypertension in children: association with target-organ damage. Pediatr Nephrol 20(8):1151–1155

    Article  Google Scholar 

  • Torok K, Palfi A, Szelenyi Z, Molnar D (2008) Circadian variability of blood pressure in obese children. Nutr Metab Cardiovasc Dis 18(6):429–435

    Article  CAS  Google Scholar 

  • Urbina E, Alpert B, Flynn J, Hayman L, Harshfield GA, Jacobson M, Mahoney L, McCrindle B, Mietus-Snyder M, Steinberger J, Daniels S (2008) Ambulatory blood pressure monitoring in children and adolescents: recommendations for standard assessment. A scientific statement from the American Heart Association. Atherosclerosis, Hypertension, and Obesity in Youth Committee of the Council on Cardiovascular Disease in the Young and the Council for High Blood Pressure Research. Hypertension 52:433–451

    Article  CAS  Google Scholar 

  • Varda NM, Gregoric A (2005) Twenty-four-hour ambulatory blood pressure monitoring in infants and toddlers. Pediatr Nephrol 20:798–802

    Article  Google Scholar 

  • Westerstahl M, Forss M, Persson L, Bouma K, Gustavsson T, Wühl E, Krmar RT (2018) Hypertension outcomes and cardiovascular status in young adults with childhood-diagnosed white coat hypertension. Arch Dis Child 103(1):113–114

    Article  Google Scholar 

  • Whelton PK, Carey RM, Aronow WS, Casey DE Jr, Collins KJ, Dennison Himmelfarb C, DePalma SM, Gidding S, Jamerson KA, Jones DW, MacLaughlin EJ, Muntner P, Ovbiagele B, Smith SC Jr, Spencer CC, Stafford RS, Taler SJ, Thomas RJ, Williams KA Sr, Williamson JD, Wright JT Jr (2018) 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and Management of High Blood Pressure in adults: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Hypertension 71(6):e13–e115

    CAS  Google Scholar 

  • Williams B, Mancia G, Spiering W, Agabiti Rosei E, Azizi M, Burnier M, Clement DL, Coca A, de Simone G, Dominiczak A, Kahan T, Mahfoud F, Redon J, Ruilope L, Zanchetti A, Kerins M, Kjeldsen SE, Kreutz R, Laurent S, Lip GYH, McManus R, Narkiewicz K, Ruschitzka F, Schmieder RE, Shlyakhto E, Tsioufis C, Aboyans V, Desormais I, ESC Scientific Document Group (2018) 2018 ESC/ESH guidelines for the management of arterial hypertension. Eur Heart J 39(33):3021–3104

    Article  Google Scholar 

  • Wolfenstetter A, Simonetti GD, Poschl J, Schaefer F, Wühl E (2012) Altered cardiovascular rhythmicity in children born small for gestational age. Hypertension 60(3):865–870

    Article  CAS  Google Scholar 

  • Wühl E, Witte K, Soergel M, Mehls O, Schaefer F, German Working Group on Pediatric Hypertension (2002) Distribution of 24-h ambulatory blood pressure in children: normalized reference values and role of body dimensions. J Hypertens 20(10):1995–2007

    Article  Google Scholar 

  • Wühl E, Hadtstein C, Mehls O, Schaefer F, Escape Trial Group (2004) Home, clinic, and ambulatory blood pressure monitoring in children with chronic renal failure. Pediatr Res 55:492–497

    Article  Google Scholar 

  • Wühl E, Hadtstein C, Mehls O, Schaefer F, Escape Trial Group (2005) Ultradian but not circadian blood pressure rhythms correlate with renal dysfunction in children with chronic renal failure. J Am Soc Nephrol 16(3):746–754

    Article  Google Scholar 

  • Wühl E, Trivelli A, Picca S, Litwin M, Peco-Antic A, Zurowska A, Testa S, Jankauskiene A, Emre S, Caldas-Afonso A, Anarat A, Niaudet P, Mir S, Bakkaloglu A, Enke B, Montini G, Wingen AM, Sallay P, Jeck N, Berg U, Caliskan S, Wygoda S, Hohbach-Hohenfellner K, Dusek J, Urasinski T, Arbeiter K, Neuhaus T, Gellermann J, Drozdz D, Fischbach M, Mîller K, Wigger M, Peruzzi L, Mehls O, Schaefer F (2009) Strict blood pressure control and renal failure progression in children. The ESCAPE Trial Group. N Engl J Med 361:1639–1650

    Article  Google Scholar 

  • Yip GW, Li AM, So HK, Choi KC, Leung LC, Fong NC, Lee KW, Li SP, Wong SN, Sung RY (2014) Oscillometric 24-h ambulatory blood pressure reference values in Hong Kong Chinese children and adolescents. J Hypertens 32(3):606–619

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Elke Wühl .

Editor information

Editors and Affiliations

Section Editor information

Rights and permissions

Reprints and permissions

Copyright information

© 2023 Springer Nature Switzerland AG

About this entry

Check for updates. Verify currency and authenticity via CrossMark

Cite this entry

Wühl, E. (2023). Ambulatory Blood Pressure Monitoring Methodology and Norms in Children. In: Flynn, J.T., Ingelfinger, J.R., Brady, T.M. (eds) Pediatric Hypertension. Springer, Cham. https://doi.org/10.1007/978-3-031-06231-5_44

Download citation

  • DOI: https://doi.org/10.1007/978-3-031-06231-5_44

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-031-06230-8

  • Online ISBN: 978-3-031-06231-5

  • eBook Packages: MedicineReference Module Medicine

Publish with us

Policies and ethics