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Drug Delivery with Porous Silicon

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Handbook of Porous Silicon

Abstract

Biodegradable porous silicon is under preclinical assessment for a range of drug delivery applications, and in this updated review, data is now available on more than 30 active pharmaceutical ingredients (API). Studies to date on oral, subcutaneous, intravenous, intravitreal, and intratumoral modes of delivery are covered. Sustained delivery of an increasing range of biological actives, like peptides and antibodies, is under evaluation, as are bioavailability enhancements for small hydrophobic APIs. Both the merits and existing challenges of this nanostructured carrier are raised.

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  1. Department of Physics and Astronomy, University of Turku, 20014, Turku, Finland

    Jarno Salonen

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  1. Malvern Hills Science Park, Chief Scientific Officer, Intrinsiq Mate, Malvern, Worcestershire, United Kingdom

    Leigh Canham

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Salonen, J. (2016). Drug Delivery with Porous Silicon. In: Canham, L. (eds) Handbook of Porous Silicon. Springer, Cham. https://doi.org/10.1007/978-3-319-04508-5_91-2

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  1. Latest

    Drug Delivery with Porous Silicon
    Published:
    27 December 2016

    DOI: https://doi.org/10.1007/978-3-319-04508-5_91-2

  2. Original

    Drug Delivery with Porous Silicon
    Published:
    06 May 2014

    DOI: https://doi.org/10.1007/978-3-319-04508-5_91-1

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