Definition
Narcolepsy is classified in the ICSD-3 under central disorders of hypersomnolence. With the ICSD-3 narcolepsy is divided into narcolepsy type 1 and narcolepsy type 2 rather than narcolepsy with and without cataplexy. Narcolepsy type 1 is caused by a deficiency of hypothalamic hypocretin signaling. Patients show low or undetectable hypocretin-1 in CSF. Some patients with narcolepsy type 2 will have low or undetectable hypocretin-1 in CSF and should be reclassified as narcolepsy type 1 even if cataplexy is absent. Underlying causes in other patients with narcolepsy type 2 are unknown.
Cross-References
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References and Readings
American Academy of Sleep Medicine. (2014). International classification of sleep disorders (3rd ed.). Chicago: American Academy of Sleep Medicine.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer International Publishing AG, part of Springer Nature
About this entry
Cite this entry
Locke, D. (2018). Narcolepsy. In: Kreutzer, J.S., DeLuca, J., Caplan, B. (eds) Encyclopedia of Clinical Neuropsychology. Springer, Cham. https://doi.org/10.1007/978-3-319-57111-9_260
Download citation
DOI: https://doi.org/10.1007/978-3-319-57111-9_260
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-57110-2
Online ISBN: 978-3-319-57111-9
eBook Packages: Behavioral Science and PsychologyReference Module Humanities and Social SciencesReference Module Business, Economics and Social Sciences