Definition
A superfamily of gelsolin-like proteins that has a conserved modular motif. Gelsolin is the founding member; other members include villin, scinderin, adseverin, supervillin, CapG, and flightless I. With the exception of flightless I, all are shown to be Ca2+-activated actin severing and/or binding proteins. Some of these proteins have also been implicated in transcriptional regulation.
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© 2011 Springer-Verlag Berlin Heidelberg
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(2011). Gelsolin Family. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-16483-5_2359
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DOI: https://doi.org/10.1007/978-3-642-16483-5_2359
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Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-16482-8
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