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Calcium Phosphate–Derived Biomaterials

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Encyclopedia of Biophysics

Introduction

Although bone tissue possesses the capacity for regenerative growth, the bone repair process is impaired in many clinical and pathological situations. Large bone loss caused by trauma and tumor resection and/or aging, require reconstructive surgery and/or bone regeneration. At present, bone surgeons have three different possibilities when it comes to replacing bone.

Autogenous bone grafts are considered as the gold standard for bone replacement, in spite of large pain, septic complications, limited amount harvested from the iliac crest or other sites. Allogenic bone grafts obtained from tissue banks also have limitations because of the possible transmission of nonconventional agents or viruses and the risk of immunological incompatibility

Alloplastic Bone substitutes are produced in various compositions and shapes (Fig. 1). These biomaterials can be used alone to fill bone cavities, serving as a scaffold for bone regeneration from the peri-implant region. Bone substitutes...

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Abbreviations

CaP:

Calcium Phosphate

HA:

Hydroxyapatite

CHA:

Carbonated Hydroxyapatite

TCP:

Tricalcium Phosphate

BCP:

Biphasic Calcium Phosphate

MBCP:

Micro Macroporous Biphasic Calcium Phosphate

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Acknowledgment

The authors thanks all the collaborators involved in the studies cited performed in Nantes University and INSERM EMI 99 03, Nantes Hospital, Nantes Microscopy SC3M department, and New York University College of Dentistry. This study was supported by FP7 framework EU program GAMBA NMP-2009-2.3-1

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Authors and Affiliations

  1. Faculty of Dental Surgery, INSERM, University of Nantes, Nantes, France

    Guy Daculsi & Thomas Miramond

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  1. Guy Daculsi
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  2. Thomas Miramond
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Corresponding author

Correspondence to Guy Daculsi .

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Editors and Affiliations

  1. Department of Biochemistry, University of Leicester, Leicester, UK

    Gordon C. K. Roberts

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© 2013 European Biophysical Societies' Association (EBSA)

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Daculsi, G., Miramond, T. (2013). Calcium Phosphate–Derived Biomaterials. In: Roberts, G.C.K. (eds) Encyclopedia of Biophysics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-16712-6_698

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