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Stilbenoids

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Natural Products

Abstract

Stilbenoids are a class of plant phenolics containing C6–C2–C6 unit in their structures and classified into five groups, covering stilbenes, oligostilbenes, bibenzyls, bisbibenzyls, and phenanthrenes. They have been a hot research topic for their intricate structures and diverse biological activities. Resveratrol and combretastatin A-4 are the star compounds due to their potent cardioprotective, chemopreventive, and antitumor properties and have the potential to be developed as new drugs. The stilbenoids do not enjoy a wide distribution and are only found in special genus. Although the constituent unit is simple, the structures of stilbenoids highlight the chemical diversity by different substitutes and various oligomeric styles. In a biogenesis viewpoint, they are formed by a branch of the flavonoid biosynthetic pathway. This chapter provides a summary of the occurrence, phytochemisty, biosynthesis, and biological aspects of the stilbenoids.

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Authors and Affiliations

  1. Department of Natural Products Chemistry, School of Pharmaceutical Sciences, Shandong University, 250012, Jinan, China

    Tao Shen, Xiao-Ning Wang & Prof. Hong-Xiang Lou

  2. College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, 300071, Tianjin, China

    Chun-Feng Xie

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  1. Tao Shen
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  2. Chun-Feng Xie
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  3. Xiao-Ning Wang
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  4. Prof. Hong-Xiang Lou
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  1. Botany Department, M.L. Sukhadia University, Durga Nursery Road, Udaipur, 313001, Rajasthan, India

    Kishan Gopal Ramawat

  2. Institute of Vine and Wine Sciences, Biological-Active Plant Substances Study, University of Bordeaux, 210 Chemin de Leysotte CS 50008, Villenave d'Ornon, 33882, France

    Jean-Michel Mérillon

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Shen, T., Xie, CF., Wang, XN., Lou, HX. (2013). Stilbenoids. In: Ramawat, K., Mérillon, JM. (eds) Natural Products. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-22144-6_63

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