Skip to main content

Tobacco Carcinogenesis

  • Living reference work entry
  • First Online:
Encyclopedia of Cancer
  • 28 Accesses

Definition

Refers to cancer induction by tobacco products and their constituents in laboratory animals and humans.

Characteristics

Tobacco Products and Human Cancer

Worldwide tobacco use continues to be immense and pervasive. According to estimates by the World Health Organization, there are about 1.3 billion smokers in the world and millions of smokeless tobacco users. Cigarette smoking causes well over one million cancer deaths annually worldwide and accounts for 26 % of all cancer mortality in developed countries. In addition to lung cancer (Lung Cancer and Smoking Behavior), cigarette smoking causes the following types of cancer: oral cavity cancer, larynx cancer, esophageal cancer, nasal cavity cancer, stomach cancer, liver cancer, renal cancer, ureter cancer, cervix cancer, and myeloid leukemia. Secondhand tobacco smoke causes lung cancer in nonsmokers, although the risk is less than in smokers. Smokeless tobacco products, such as moist snuff used orally, are accepted causes of...

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

References

  • Hecht SS (1999) Tobacco smoke carcinogens and lung cancer. J Natl Cancer Inst 91:1194–1210

    Article  CAS  PubMed  Google Scholar 

  • Hecht SS (2003) Tobacco carcinogens, their biomarkers, and tobacco-induced cancer. Nat Rev Cancer 3:733–744

    Article  CAS  PubMed  Google Scholar 

  • Hecht SS (2005) Carcinogenicity studies of inhaled cigarette smoke in laboratory animals: old and new. Carcinogenesis 26:1488–1492

    Article  CAS  PubMed  Google Scholar 

  • International Agency for Research on Cancer (2004) Tobacco smoke and involuntary smoking. In: IARC monographs on the evaluation of carcinogenic risks to humans, vol 89. IARC, Lyon, pp 33–1452

    Google Scholar 

  • International Agency for Research on Cancer (2007) Smokeless tobacco and tobacco-specific nitrosamines. In: IARC monographs on the evaluation of carcinogenic risks to humans, vol 89. IARC, Lyon (in press)

    Google Scholar 

  • U.S. Department of Health and Human Services (2014) The Health Consequences of Smoking-50 years of Progress, A Report of the Surgeon General, pp 148–151

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Stephen S. Hecht .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer-Verlag Berlin Heidelberg

About this entry

Cite this entry

Hecht, S.S. (2015). Tobacco Carcinogenesis. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_5846-2

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-27841-9_5846-2

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-27841-9

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

Publish with us

Policies and ethics