Skip to main content

Bone Tumors

  • Living reference work entry
  • First Online:
Encyclopedia of Cancer
  • 120 Accesses

Synonyms

Bone neoplasms; Bone sarcomas

Definition

Bone tumors are space-occupying lesions arising in bone that are usually derived from primitive connective tissue elements.

They constitute a diverse group of neoplasms that are collectively less common than those of almost all other body sites. Malignant primary bone tumors have an approximate incidence one new malignant bone tumor per 100,000 individuals per year. Since the incidence of benign bone tumors is about half that of malignant tumors, the average aggregate incidence of all bone tumors is about one in 67,000 persons per year.

With a few notable exceptions, bone tumors have a predilection for individuals in the second and third decade; there is a second, smaller peak of incidence in the sixth and seventh decade. In most large series of bone tumors, there is a slight male predominance. Each tumor type has a characteristic range age, skeletal distribution, and sometimes sex and racial predilection.

Characteristics

Etiology

While...

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

References

  • Dorfman HD, Czerniak B, Kotz R (2002) WHO classification of tumours of bone: introduction. In: Fletcher CDM, Bridge JA, Hogendoorn DCW, Mertens F (eds) Pathology and genetics of tumours of soft tissue and bone, WHO Classification of Tumours of Soft Tissue and Bone (IARC: Lyon 2013). pp. 384–385, 390–392.

    Google Scholar 

  • Klein MJ (2005) Radiographic correlation in orthopedic pathology. Adv Anat Pathol 12(4):155–179

    Article  PubMed  Google Scholar 

  • Klein MJ, Siegal GP (2006) Osteosarcoma: anatomic and histological variants. Am J Clin Pathol 125(4):555–581

    Article  PubMed  Google Scholar 

  • Unni KK, Inwards CY, Bridge JA (2005) Tumors of the bones and joints, AFIP Atlas of tumor pathology, 4th series, fascicle 2. ARP Press, Silver Spring

    Google Scholar 

See Also

  • (2012) Dedifferentiation. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1072. doi:10.1007/978-3-642-16483-5_1547

    Google Scholar 

  • (2012) Ectodermal. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1209. doi:10.1007/978-3-642-16483-5_1808

    Google Scholar 

  • (2012) Enchondroma. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1221. doi:10.1007/978-3-642-16483-5_1866

    Google Scholar 

  • (2012) Endodermal. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1232. doi:10.1007/978-3-642-16483-5_1877

    Google Scholar 

  • (2012) Fibrous dysplasia. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1403. doi:10.1007/978-3-642-16483-5_2183

    Google Scholar 

  • (2012) Hemangioendothelioma. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1640. doi:10.1007/978-3-642-16483-5_2612

    Google Scholar 

  • (2012) Hemangioma. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1640. doi:10.1007/978-3-642-16483-5_2613

    Google Scholar 

  • (2012) Idiopathic bone infarction. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1804. doi:10.1007/978-3-642-16483-5_2942

    Google Scholar 

  • (2012) Mesoderm. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2240. doi:10.1007/978-3-642-16483-5_3645

    Google Scholar 

  • (2012) Paget disease. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2758. doi:10.1007/978-3-642-16483-5_4345

    Google Scholar 

  • (2012) Rothmund-Thomson syndrome. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 3322. doi:10.1007/978-3-642-16483-5_5128

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Michael J. Klein .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer-Verlag Berlin Heidelberg

About this entry

Cite this entry

Klein, M.J. (2014). Bone Tumors. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_689-3

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-27841-9_689-3

  • Received:

  • Accepted:

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-27841-9

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

Publish with us

Policies and ethics