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Acridone alkaloids of callus tissue ofRuta graveolens

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Abstract

A strain of tissue of common rue of root origin (index of the strain R-4) has been obtained which produces up to 3% (of the dry weight) of acridone alkaloids. It has been shown by physicochemical methods that the combined alkaloids consist mainly of 1-hydroxy-N-methylacridone, rutacridone, and 1-hydroxy-3-methoxy N-methylacridone (0.28, 0.81, and 2.41 mg/g dry weight of tissue, respectively). Strain R-4 is a good model for the study of little-known steps in the biogenesis of the acridone alkaloids.

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Authors
  1. I. N. Kuzovkina
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  2. L. D. Kislov
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  3. M. N. Zhivopistseva
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  4. Zs. Rozsa
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  5. K. Szendrei
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Additional information

K. A. Timiryazev Institute of Plant Physiology, Academy of Sciences of the USSR, Moscow. Institute of Pharmacognosy, Medical University of Szeged, Hungarian Academy of Sciences. Translated from Khimiya Prirodnykh Soedinenii, No. 6, pp. 758–761, November–December, 1934.

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Kuzovkina, I.N., Kislov, L.D., Zhivopistseva, M.N. et al. Acridone alkaloids of callus tissue ofRuta graveolens . Chem Nat Compd 20, 716–719 (1984). https://doi.org/10.1007/BF00580032

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  • DOI: https://doi.org/10.1007/BF00580032

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