Summary
Phosphonic acid analogue of forfenicine, amino (p-formylbenzyl)-phosphonic acid, was synthesized and evaluated as antibacterial agent. As indicated by disc diffusion test this compound was found to inhibit significantly the growth ofBacillus subtilis andStaphylococcus aureus and moderately the growth ofEscherichia coli. Resistance ofPseudomonas fluorescens to the action of the aminophosphonate may result from the ability of the strain to degrade this compound.
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Czerwonka, A., Lejczak, B., Boduszek, B. et al. Phosphonic acid analogue of forfenicine — synthesis, antibacterial activity and degradation byPseudomonas fluorescens . Amino Acids 12, 101–106 (1997). https://doi.org/10.1007/BF01373431
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DOI: https://doi.org/10.1007/BF01373431