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Androgens and vascular function

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References

  1. Schachinger V, Britten MB, Zeiher AM. Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease. Circulation 2000, 101: 1899–906.

    Article  PubMed  CAS  Google Scholar 

  2. Anderson TJ, Uehata A, Gerhard MD, et al. Close relation of endothelial function in the human coronary and peripheral circulations. J Am Coll Cardiol 1995, 26: 1235–41.

    Article  PubMed  CAS  Google Scholar 

  3. Jaffe EA. Cell biology of endothelial cells. Hum Pathol 1987, 18: 234–9.

    Article  PubMed  CAS  Google Scholar 

  4. Tunstall-Pedoe H, Kuulasmaa K, Amouyel P, Arveiler D, Rajakangas AM, Pajak A. Myocardial infarction and coronary deaths in the World Health Organization MONICA Project. Registration procedures, event rates, and casefatality rates in 38 populations from 21 countries in four continents. Circulation 1994, 90: 583–612.

    Article  PubMed  CAS  Google Scholar 

  5. Lin AL, Gonzalez R, Shain SA. Androgen directs apparent cytoplasmic and nuclear distribution of rat cardiovascular androgen receptors. Arteriosclerosis 1985, 5: 659–67.

    Article  PubMed  CAS  Google Scholar 

  6. Higashiura K, Mathur RS, Halushka PV. Gender-related differences in androgen regulation of thromboxane A2 receptors in rat aortic smooth-muscle cells. J Cardiovasc Pharmacol 1997, 29: 311–5.

    Article  PubMed  CAS  Google Scholar 

  7. Chou TM, Sudhir K, Hutchison SJ. Testosterone induces dilatation of canine coronary conductance and resistance arteries in vivo. Circulation 1996, 94: 614–9.

    Article  Google Scholar 

  8. Herman SM, Robinson JT, McCredie RJ, Adams MR, Boyer MJ, Celermajer DS. Androgen deprivation is associated with enhanced endothelium-dependent dilatation in adult men. Arterioscler Thromb Vasc Biol 1997, 17: 2004–9.

    Article  PubMed  CAS  Google Scholar 

  9. McCrohon JA, Walters WA, Robinson JT, et al. Arterial reactivity is enhanced in genetic males taking high dose estrogens. J Am Coll Cardiol 1997, 29: 1432–6.

    Article  PubMed  CAS  Google Scholar 

  10. Ong PJ, Patrizi G, Chong WC, Webb CM, Hayward CS, Collins P. Testosterone enhances flow-mediated brachial artery reactivity in men with coronary artery disease. Am J Cardiol 2000, 85: 269–720.

    Article  PubMed  CAS  Google Scholar 

  11. Thompson PD, Ahlberg AW, Moyna NM, et al. Effect of intravenous testosterone on myocardial ischemia in men with coronary artery disease. Am Heart J 2002, 143: 249–56.

    Article  PubMed  CAS  Google Scholar 

  12. Ly LP, Jimenez M, Zhuang TN, Celermajer DS, Conway AJ, Handelsman DJ. A double-blind, placebo-controlled, randomized clinical trial of transdermal dihydrotestosterone gel on muscular strength, mobility, and quality of life in older men with partial androgen deficiency. J Clin Endocrinol Metab 2001, 86: 4078–88

    Article  PubMed  CAS  Google Scholar 

  13. Zitzmann M, Brune M, Nieschlag E. Vascular reactivity in hypogonadal men is reduced by androgen substitution. J Clin Endocrinol Metab 2002, 87: 5030–7.

    Article  PubMed  CAS  Google Scholar 

  14. Zitzmann M, Brune M, Vieth V, Nieschlag E. Monitoring bone density in hypogonadal men by quantitative phalangeal ultrasound. Bone 2002, 31: 422–9.

    Article  PubMed  CAS  Google Scholar 

  15. Zitzmann M, Brune M, Kornmann B, et al. The CAG repeat polymorphism in the AR gene affects high density lipoprotein cholesterol and arterial vasoreactivity. J Clin Endocrinol Metab 2001, 86: 4867–73.

    Article  PubMed  CAS  Google Scholar 

  16. Zitzmann M, Gromoll J, von Eckardstein A, Nieschlag E. The CAG repeat polymorphism in the androgen receptor gene modulates body fat mass and serum concentrations of leptin and insulin in men. Diabetologia 2003, 46: 31–9.

    PubMed  CAS  Google Scholar 

  17. Zitzmann M, Junker R, Kamischke A, Nieschlag E. Contraceptive steroids influence the hemostatic activation state in healthy men. J Androl 2002, 23: 503–11.

    PubMed  CAS  Google Scholar 

  18. Wu FCW, von Eckardstein A. Androgens and coronary artery disease. Endocr Rev 2003, 24: 183–217.

    Article  PubMed  CAS  Google Scholar 

  19. Nieschlag E, Nieschlag S, Behre HM. Lifespan and testosterone. Nature 1993, 366: 215.

    Article  PubMed  CAS  Google Scholar 

  20. Ebrahim S, Smith GD, May M, Yarnell J. Shaving, coronary heart disease, and stroke: the Caerphilly Study. Am J Epidemiol 2003, 157: 234–8.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Institute of Reproductive Medicine, University of Münster, Münster, Germany, Domagkstr. 11, D-48129

    M. Zitzmann &  E. Nieschlag

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  1. M. Zitzmann
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  2. E. Nieschlag
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Correspondence to E. Nieschlag.

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Zitzmann, M., Nieschlag, E. Androgens and vascular function. J Endocrinol Invest 26, 767–769 (2003). https://doi.org/10.1007/BF03347363

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