Skip to main content
SpringerLink
Log in

A rare case of a molecular “adult-type” diffuse astrocytoma arising in a child

  • Letter to the Editor
  • Published:
Child's Nervous System Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

References

  1. Cancer Genome Atlas Research Network (2015) Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas. N Engl J Med 372(26):2481–2498. https://doi.org/10.1056/NEJMoa1402121

    Article  CAS  Google Scholar 

  2. Zhang J, Wu G, Miller CP, Tatevossian RG, Dalton JD, Tang B, Orisme W, Punchihewa C, Parker M, Qaddoumi I, Boop FA, Lu C, Kandoth C, Ding L, Lee R, Huether R, Chen X, Hedlund E, Nagahawatte P, Rusch M, Boggs K, Cheng J, Becksfort J, Ma J, Song G, Li Y, Wei L, Wang J, Shurtleff S, Easton J, Zhao D, Fulton RS, Fulton LL, Dooling DJ, Vadodaria B, Mulder HL, Tang C, Ochoa K, Mullighan CG, Gajjar A, Kriwacki R, Sheer D, Gilbertson RJ, Mardis ER, Wilson RK, Downing JR, Baker SJ, Ellison DW, St. Jude Children’s Research Hospital–Washington University Pediatric Cancer Genome Project (2013) Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas. Nat Genet 45(6):602–612. https://doi.org/10.1038/ng.2611

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Pollack IF, Hamilton RL, Sobol RW et al (2011) IDH1 mutations are common in malignant gliomas arising in adolescents: a report from the Children’s Oncology Group. Childs Nerv Syst 27(1):87–94. https://doi.org/10.1007/s00381-010-1264-1

    Article  PubMed  Google Scholar 

  4. De Carli E, Wang X, Puget S (2009) IDH1 and IDH2 mutations in glioma. N Engl J Med 360(21):2248. https://doi.org/10.1056/NEJMc090593

    Article  PubMed  Google Scholar 

  5. Ferris SP, Goode B, Joseph NM, Kline CN, Samuel D, Gupta N, Bollen A, Perry A, Mueller S, Solomon DA (2016) IDH1 mutation can be present in diffuse astrocytomas and giant cell glioblastoma of young children under 10 years of age. Acta Neuropathol 132(1):153–155. https://doi.org/10.1007/s00401-016-1579-4

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Anatomic Pathology, University Hospital of Udine, Piazzale S. Maria della Misericordia, 33100, Udine, Italy

    Enrico Pegolo & Nastassia Nardini

  2. Department of Pediatrics, S. Maria della Misericordia University Hospital, University of Udine, Piazzale S. Maria della Misericordia, 33100, Udine, Italy

    Raffaello Tosolini, Eva Passone & Paola Cogo

Authors
  1. Enrico Pegolo
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Raffaello Tosolini
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Nastassia Nardini
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Eva Passone
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Paola Cogo
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Enrico Pegolo.

Ethics declarations

Conflict of interest

On behalf of all authors, the corresponding author states that there is no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Pegolo, E., Tosolini, R., Nardini, N. et al. A rare case of a molecular “adult-type” diffuse astrocytoma arising in a child. Childs Nerv Syst 34, 191–193 (2018). https://doi.org/10.1007/s00381-017-3680-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00381-017-3680-y

Search

Navigation