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Intracytoplasmic sperm injection (ICSI) in unexplained and stage I endometriosis-associated infertility after fertilization failure with in vitro fertilization (IVF)

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Abstract

Purpose: To investigate possible differences between unexplained and stage I endometriosis-associated infertility in ICSI cycles conducted after low fertilization (<20%) in preceding IVF cycles with normal semen parameters.

Methods: Retrospective cohort study consisting of patients with unexplained (n=48) and stage I endometriosis-associated infertility (n=43) with a minimum of one IVF cycle with <20% fertilized oocytes and normal semen quality, treated with ICSI from January 1997 to January 2006. Age matched male factor infertility patients (n=91) were used as controls.

Results: Diploid fertilization rate was significantly lower in the stage I endometriosis-associated infertility group compared to the unexplained infertility group. Score of the transferred embryos, implantation rate, pregnancy rate and outcome were similar in the two groups.

Conclusions: ICSI appears to be an efficient treatment option after fertilization failure with IVF in unexplained and stage I endometriosis-associated infertility.

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Authors and Affiliations

  1. Department of Obstetrics and Gynaecology, Rikshospitalet–Radiumhospitalet Medical Center, Sognsvannsveien 20, 0027, Oslo, Norway

    Anne K. Omland, Sverre Bjercke, Gudvor Ertzeid, Peter Fedorcsák, Nan B. Oldereid, Ritsa Storeng, Thomas Åbyholm & Tom Tanbo

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  1. Anne K. Omland
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  2. Sverre Bjercke
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  3. Gudvor Ertzeid
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  4. Peter Fedorcsák
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  5. Nan B. Oldereid
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  6. Ritsa Storeng
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  7. Thomas Åbyholm
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  8. Tom Tanbo
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Correspondence to Anne K. Omland.

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Omland, A.K., Bjercke, S., Ertzeid, G. et al. Intracytoplasmic sperm injection (ICSI) in unexplained and stage I endometriosis-associated infertility after fertilization failure with in vitro fertilization (IVF). J Assist Reprod Genet 23, 351–357 (2006). https://doi.org/10.1007/s10815-006-9060-2

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  • DOI: https://doi.org/10.1007/s10815-006-9060-2

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