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Isolation and Characterization of an Unknown Chrysosporium sp. Producing Subcutaneous Mycosis in an Immunocompromised Patient

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Abstract

We report a case of subcutaneous fungal abscess over the great toe caused by a keratinophilic fungus, an unknown Chrysosporium sp., in a 60-year-old diabetic female who was treated successfully with oral fluconazole. The fungus was isolated from aspirated pus, and septate hyphae were seen in fine needle aspiration cytology. Ovoid- to club-shaped hyaline one-celled conidia (aleuriconidia) with broad truncated bases were seen, and sequencing of ITS1-5.8S-ITS2 rDNA revealed belonging to the order Onygenales and most closely related to Chrysosporium spp. isolated from a fowl. Of the 65 species within the genus Chrysosporium, very few have been reported as pathogenic.

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Acknowledgments

We thank the staff of Centre of Advance Research in Medical Mycology, WHO Collaborating Centre, National Culture Collection of Pathogenic Fungi, Postgraduate institute of medical education and research (PGIMER), Chandigarh, India, for their assistance in identification of the fungus till species level.

Conflict of interest

The authors declare they have no conflict of interest.

Ethical standards

All procedures performed in the studies involving human participants were in accordance with the ethical standards of the institution and/or national research committee and with the Declaration of Helsinki 1964 and its amendments or comparable ethical standards.

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Informed consent was obtained.

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Authors and Affiliations

  1. Department of Microbiology, Father Muller Medical College, Mangalore, 575002, India

    Sagar Chandrakar, Meena Dias & Jutang Babat Ain Tiewsoh

  2. Department of Surgery, Father Muller Medical College, Mangalore, India

    Prathvi Shetty

  3. Mycology Unit, School of Medicine and Health Sciences, Reus, Catalonia, Spain

    Josep Guarro

Authors
  1. Sagar Chandrakar
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  2. Meena Dias
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  3. Prathvi Shetty
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  4. Jutang Babat Ain Tiewsoh
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  5. Josep Guarro
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Corresponding author

Correspondence to Sagar Chandrakar.

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Chandrakar, S., Dias, M., Shetty, P. et al. Isolation and Characterization of an Unknown Chrysosporium sp. Producing Subcutaneous Mycosis in an Immunocompromised Patient. Mycopathologia 181, 115–118 (2016). https://doi.org/10.1007/s11046-015-9883-4

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  • DOI: https://doi.org/10.1007/s11046-015-9883-4

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