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Chemical constituents of Ficus odorata

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Pharmaceutical Chemistry Journal Aims and scope

A dichloromethane extract of the leaves of Ficus odorata (Moreaceae family) contains l-sitosteryl3β-glucopyranoside-6'-O-palmitate (1), squalene (2), lutein (3), α-amyrin acetate (4), lupeol acetate (5), and β-carotene (6). The structure of 1 was elucidated by extensive 1D and 2D NMR spectroscopy. Compound 1 was tested for cytotoxicity using sulforhodamine B assay against the human lung adenocarcinoma epithelial cell line (A549), human stomach adenocarcinoma cell line (AGS), human colon adenocarcinoma (HT29) and human prostate cancer cell line (PC3). It exhibited cytotoxicity against AGS cell line with 60.28% growth inhibition

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Authors and Affiliations

  1. School of Chemical Engineering and Chemistry, Mapúa Institute of Technology, 1002, Manila, Philippines

    P.-W. Tsai & K. A. De Castro-Cruz

  2. National Research Institute of Chinese Medicine, 112, Taipei, Taiwan

    C.-C. Shen & C.-T. Chiou

  3. Chemistry Department, De La Salle University, 1004, Manila, Philippines

    C. Y. Ragasa

  4. Center for Natural Sciences and Ecological Research, De La Salle University, 1004, Manila, Philippines

    C. Y. Ragasa

Authors
  1. P.-W. Tsai
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  2. K. A. De Castro-Cruz
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  3. C.-C. Shen
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  4. C.-T. Chiou
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  5. C. Y. Ragasa
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Corresponding author

Correspondence to C. Y. Ragasa.

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Tsai, PW., De Castro-Cruz, K.A., Shen, CC. et al. Chemical constituents of Ficus odorata . Pharm Chem J 46, 225–227 (2012). https://doi.org/10.1007/s11094-012-0767-3

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  • DOI: https://doi.org/10.1007/s11094-012-0767-3

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