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Production of Gentisyl Alcohol from Phoma herbarum Endophytic in Curcuma longa L. and Its Antagonistic Activity Towards Leaf Spot Pathogen Colletotrichum gloeosporioides

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Abstract

Endophytes from medicinal plants represent a potential source of bioactive compounds. During the present investigation, fungal endophytes were isolated from turmeric (Curcuma longa), an important medicinal plant. A total of 207 endophytic fungal isolates were obtained from the rhizome of C. longa L. They were grouped into seven genera based on morphological and molecular data. The fungal endophytes of C. longa were evaluated for antifungal activity against Colletotrichum gloeosporioides, the causal organism of leaf spot of turmeric. The disease is a major cause for economic loss in turmeric cultivation. Endophytic Phoma herbarum showed significant activity against C. gloeosporioides and was therefore selected for further studies. A compound gentisyl alcohol was isolated from P. herbarum which showed effective antagonism against C. gloeosporioides. The organism could therefore be used as a biocontrol agent against C. gloeosporioides.

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Acknowledgments

The authors acknowledge Department of Biotechnology, Government of India, for the funding and facilities. Ms. Suruchi is grateful to DBT for the fellowship (DBT-JRF/2011-12/252). Bioinformatics Centre at School of Biotechnology and instrumentation facility under FIST (DST, GOI) and SAP (UGC, New Delhi)) programmes are also acknowledged.

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  1. Fungal Biotechnology Laboratory, School of Biotechnology, University of Jammu, Jammu, Jammu and Kashmir, 180006, India

    Suruchi Gupta, Sanjana Kaul & Manoj K. Dhar

  2. CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu, Jammu and Kashmir, 180001, India

    Baljinder Singh & Ram A. Vishwakarma

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  1. Suruchi Gupta
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Gupta, S., Kaul, S., Singh, B. et al. Production of Gentisyl Alcohol from Phoma herbarum Endophytic in Curcuma longa L. and Its Antagonistic Activity Towards Leaf Spot Pathogen Colletotrichum gloeosporioides . Appl Biochem Biotechnol 180, 1093–1109 (2016). https://doi.org/10.1007/s12010-016-2154-0

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