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Oxidized guar gum–ZnO hybrid nanostructures: synthesis, characterization and antibacterial activity

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Abstract

In the present study, guar gum (GG) and oxidized guar gum (OGG) have been used for modulating the antibacterial activity of ZnO. Oxidized guar gum–zinc oxide (OGG–ZnO) or guar gum–zinc oxide (GG–ZnO) nanostructures were synthesized by adding aqueous ammonia to zinc acetate solution in the presence of OGG or GG, respectively. OGG could significantly enhance the antibacterial activity of ZnO for a range of Gram-negative and Gram-positive bacterial strains and this enhancement was most pronounced for Bacillus subtilis and Salmonella typhi. At the same time, GG–ZnO nanostructures were found to be less bioactive than the pure ZnO for the same strains. TEM analysis revealed that optimum OGG–ZnO nanostructure (Z4) is of ~ 200 nm size, oblong in shape, and has slightly clustered texture, while XRD confirmed its crystalline structure with hexagonal phase. The extra surface oxygen species (thus oxygen deficiency) has been assigned for better antibacterial behavior of OGG–ZnO. The study may be extended for other polysaccharide/derivatives to obtain ZnO nanostructures with enhanced antibacterial properties.

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Acknowledgements

Authors thank MNIT, Jaipur, for FTIR, SEM and TEM instrumental facilities. Dr. Lokendra Kumar, Physics Department of University of Allahabad, is acknowledged for XRD facility. Author LMD thanks U.G.C, New Delhi, for the financial support to carry out this work.

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  1. Department of Chemistry, University of Allahabad, Allahabad, 211002, India

    Vandana Singh, Lalit Mohan Dwivedi, Kirti Baranwal & Sugandha Asthana

  2. Department of Biotechnology, University of Allahabad, Allahabad, 211002, India

    Lalit Mohan Dwivedi, Kirti Baranwal, Sugandha Asthana & Shanthy Sundaram

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  1. Vandana Singh
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  2. Lalit Mohan Dwivedi
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Correspondence to Vandana Singh.

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Singh, V., Dwivedi, L.M., Baranwal, K. et al. Oxidized guar gum–ZnO hybrid nanostructures: synthesis, characterization and antibacterial activity. Appl Nanosci 8, 1149–1160 (2018). https://doi.org/10.1007/s13204-018-0747-3

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