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Oligometastatic Disease in Lung Cancer for Surgeons: An Update

  • Thoracic Surgery (G. Rocco & M. Scarci, Section Editors)
  • Published:
Current Surgery Reports Aims and scope Submit manuscript

Abstract

Purpose of review

Stage IV non-small cell lung cancer (NSCLC) is a heterogenic disease with constant challenges for physicians. In the case of oligometastatic disease, surgery has a crucial role. In selected cases of a possible indolent progression of the malignancy, a surgical approach is recommended to control the disease. The management of this subset of patients should be performed in a multidisciplinary team in order to define the best strategy for each patient.

Recent findings

The implementation of optimizing surgical management has demonstrated better outcomes in terms of long-term survival with no detrimental impact in morbidity and mortality. The progressive identification and use of molecular targeted therapies and immunotherapy has led to considerable improvements in responses among patients with advanced, unresectable NSCLC. As a result, the new concept of oligoprogressive disease is another demanding task to manage for oncologists and surgeons.

Summary

Further studies are needed in order to best select patients, and to identify the best strategy to adopt also with the association among surgery, radiotherapy and oncological drugs.

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Authors and Affiliations

  1. Oncology Unit, ASST San Gerardo Hospital, Via G. B. Pergolesi 33, 20052, Monza, Italy

    Francesca Colonese, Stefania Canova & Diego Luigi Cortinovis

  2. Department of Thoracic Surgery, European Institute of Oncology, Milan, Italy

    Francesco Petrella

  3. Department of Oncology and Emato-oncology, Università degli Studi di Milano, Milan, Italy

    Francesco Petrella

Authors
  1. Francesca Colonese
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  2. Stefania Canova
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  3. Francesco Petrella
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  4. Diego Luigi Cortinovis
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Corresponding author

Correspondence to Francesca Colonese.

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The authors declare no conflicts of interest relevant to this manuscript.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Additional information

This article is part of the Topical collection on Thoracic Surgery.

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Colonese, F., Canova, S., Petrella, F. et al. Oligometastatic Disease in Lung Cancer for Surgeons: An Update. Curr Surg Rep 6, 6 (2018). https://doi.org/10.1007/s40137-018-0203-z

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  • DOI: https://doi.org/10.1007/s40137-018-0203-z

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