Abstract
Objective
To investigate the effectiveness and safety of acupuncture in persistent allergic rhinitis (PAR).
Design
Randomised, single-blind, sham-controlled trial conducted from May 2004 to February 2005.
Participants and intervention
80 patients with PAR (age, 16–70 years) were randomly assigned to receive real or sham acupuncture. After a 1-week baseline period, participants were tre ated twice weekly for 8 weeks and followed up for another 12 weeks.
Main outcome measures
Nasal obstruction, sneezing, rhinorrhoea and nasal itch were each self-assessed daily on a 5-point scale, and scores were aggregated weekly. The sum of the symptom scores (total nasal symptom score, TNSS) was also determined. A secondary outcome was use of PAR relief medication.
Results
After 8 weeks’ treatment, the weekly mean difference in TNSS from baseline was greater with real (−17.2; 95 % CI, −24.6 to −9.8) than with sham acupuncture (−4.2; 95 % CI, −11.0 to 2.7) (P = 0.01). The decrease in individual symptom score was also greater with real acupuncture for rhinorrhoea (P < 0.01) but not the other symptoms. At the end of follow-up, the greater difference in TNSS from baseline in the real acupuncture group was still apparent: real, −21.0 (95 % CI, −29.1 to −12.9) versus sham, −2.3 (95 % CI, −10.2 to 5.6) (P = 0.001). Moreover, the differences from baseline in all four individual symptom scores were greater for the real than for the sham group (P < 0.05). Real and sham acupuncture were both well tolerated.
Conclusion
Our findings suggest that acupuncture is effective in the symptomatic treatment of PAR.
Literatur
Brinkhaus B, Hummelsberger J, Kohnen R et al. Acupuncture and Chinese herbal medicine in the treatment of patients with seasonal allergic rhinitis: a randomized-controlled clinical trial. Allergy 2004; 59,9:953–960
Ng DK, Chow PY, Ming SP et al. A double-blind, randomized, placebo-controlled trial of acupuncture for the treatment of childhood persistent allergic rhinitis. Pediatrics 2004;114,5:1242–1247
Xue CC, An X, Cheung TP et al. Acupuncture for persistent allergic rhinitis: a randomised, sham-controlled trial. Med J Aust. 2007;187,6:337–341
Xue CC, English R, Zhang JJ et al. Effect of acupuncture in the treatment of seasonal allergic rhinitis: a randomized controlled clinical trial. Am. J. Chin Med. 2002; 30,1:1–11
Xue CC, Thien FC, Zhang JJ et al. Treatment for seasonal allergic rhinitis by Chinese herbal medicine: a randomized placebo controlled trial. Altern. Ther. Health Med. 2003;9,5:80–87
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Xue, C.C.L., An, X., Cheung, T.P. et al. Acupuncture for Persistent Allergic Rhinitis: a Randomised, Sham-Controlled Trial. Dtsch Z Akupunkt 51, 45–46 (2008). https://doi.org/10.1016/j.dza.2008.04.003
Published:
Issue Date:
DOI: https://doi.org/10.1016/j.dza.2008.04.003