Overview
- Editors:
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Kiyonobu Mikanagi
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Mikanagi Gotanda Hospital, Tokyo, Japan
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Kusuki Nishioka
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Tokyo Women’s Medical College, Tokyo, Japan
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William N. Kelley
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University of Michigan Medical Center, Ann Arbor, USA
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Table of contents (89 chapters)
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HGPRT Deficiencies and Lesch-Nyhan Syndrome
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- Theodore Page, William L. Nyhan
Pages 129-133
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- Shin Fujimori, Beverly L. Davidson, William N. Kelley, Thomas D. Palella
Pages 135-138
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- Beverly L. Davidson, Thomas D. Palella, Shin Fujimori, William N. Kelley
Pages 139-143
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- Surjit Singh, Ingrid Willers, Karsten Held, Werner Goedde
Pages 145-150
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- R. B. Gordon, D. T. Keough, D. G. Sculley, J. de Jersey, B. T. Emmerson, I. R. Beacham
Pages 151-154
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- D. T. Keough, R. B. Gordon, J. de Jersey, B. T. Emmerson
Pages 155-158
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- Roberta M. Palmour, Timothy W. Heshka, Frank R. Ervin
Pages 165-172
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- Manuel L. JimĂ©nez, Juan G. Puig, FelĂcitas A. Mateos, Teresa H. Ramos, Ignacio P. Castroviejo, Julio O. Vázquez
Pages 173-179
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- N. Lawrence Edwards, Michael V. Johnston, Faye S. Silverstein
Pages 181-184
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Gout and Uric Acid
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- Ching-Lang Chen, Naoyuki Kamatani, Kusuki Nishioka, Kiyonobu Mikanagi
Pages 189-195
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- Lynda G. Darlington, James T. Scott
Pages 197-204
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- Bryan T. Emmerson, Roy Axelsen, Michael Cross
Pages 205-209
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- A. Giacomello, A. Zoppini, M. L. Sorgi, V. Riccieri, C. Salerno
Pages 211-214
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- Toru Shimizu, Mineko Nishikawa, Hiroshi Matsushige
Pages 215-218
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- Kumiko Hashizume, Minoru Sasano, Makoto Goto, Nobuyuki Miyasaka, Kusuki Nishioka
Pages 219-224
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- Taddeo Anna, Morozzi Gabriella, Marcolongo Roberto
Pages 225-232
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- Maria R. Mazzoni, Gino Giannaccini, Fabio Lena, Claudia Martini, Laura Bazzichi, Maria L. Ciompi et al.
Pages 233-237
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- Enrico Marinello, Brunetta Porcelli, Daniela Vannoni, Anna Taddeo
Pages 239-242
About this book
These two volumes contain articles presented at the Vlth International Symposium on Human Purine and Pyrimidine Metabolism held in Hakone, Japan ,July 17 trough 21, 1988. The first meeting of this series of symposia convened in Tel Aviv, Israel, and since then meetings have taken place every three years in various parts of the world. The second meeting was held in Baden, Austria, the third in Madrid, Spain, the fourth in Maastricht, the Netherlands, and fifth in San Diego, California. The Vlth meeting in Hakone marked the first such symposium held in Asia. On occasion of publishing these books, I would like to describe how research in this field has evolved in Japan. Early in the 1950s, I was engaged in clinical practice treating various rheumatic diseases as an orthopedicist, and found that a substantial percentage of our patients had symptoms apparently compatible with gout. During the 1960s, the number of these gouty patients increased, and in the 1970s, research on the pathogenesis of gout was performed on the basis of approximately 2,000 cases of this disease, together with precise epidemiological studies concerning gouty and hyperuricemic individuals. Data derived from the two kinds of study had greatly changed the notion that gout was a rare disease among Japanese. My clinical studies have been succeeded by research at the molecular level on various purine metabolic abnormalities, including not only gout but also other diseases with various symptoms of wide clinical spectra.
Editors and Affiliations
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Mikanagi Gotanda Hospital, Tokyo, Japan
Kiyonobu Mikanagi
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Tokyo Women’s Medical College, Tokyo, Japan
Kusuki Nishioka
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University of Michigan Medical Center, Ann Arbor, USA
William N. Kelley